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Article
Study on Acoustic Emission and Crack Propagation Characteristics of Single-Fissured Sandstone with Different Angles Under Uniaxial Compression
The uniaxial compression tests are conducted on single-fissured sandstone with different angles, and the effect of fissure angle (β) on mechanical properties, acoustic emission (AE) features, crack propagation ch...
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Article
Nanodiamond: a promising metal-free nanoscale material in photocatalysis and electrocatalysis
Benefiting from its surface-rich functional groups, eco-friendliness, impressive electrochemical properties, excellent light absorption, structural tunability at the atomic/morphological level, and ultra-high ...
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Article
Open AccessBiomechanical evaluation of different medial column fixation patterns for valgus pilon fractures
The purpose of this study was to perform a biomechanical analysis to compare different medial column fixation patterns for valgus pilon fractures in a case-based model.
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Article
Open AccessCorrelation between serum trimethylamine-N-oxide and body fat distribution in middle-aged and older adults: a prospective cohort study
Trimethylamine-N-oxide (TMAO) is linked with obesity, while limited evidence on its relationship with body fat distribution. Herein, we investigated the associations between serum TMAO and longitudinal change ...
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Article
Exogenous melatonin enhanced cadmium stress tolerance of cucumber seedlings (Cucumis sativus L.)
Cadmium (Cd) stress seriously affects cucumber growth, yield, and quality. Melatonin (MT) can enhance plant resistance to abiotic stresses. However, studies on the mechanism of MT in enhancing plant resistance...
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Article
Open AccessStomach as the target organ of Rickettsia heilongjiangensis infection in C57BL/6 mice identified by click chemistry
Spotted fever group rickettsiae (SFGR) are obligate intracellular bacteria that cause spotted fever. The limitations of gene manipulation pose great challenges to studying the infection mechanisms of Rickettsia. ...
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Article
Application of modified cerium dioxide for photocatalytic air pollution purification
Cerium dioxide (CeO2) is a significant rare earth oxide with the merits of rich oxygen defects, specific 4f15d1 orbitals, and superior oxygen storage-release capacity in Ce4+/Ce3+ reversibility pairs, and has bee...
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Article
Open AccessLINC00525 enhances ZNF460-regulated CD24 expression through the sponge miR-125a-5p to promote malignant progression of breast cancer
CD24 is a highly glycosylated glycosylphosphatidylinositol anchored membrane protein that plays an important role in tumor progression. The aim of this study was to investigate the effect of abnormal expressio...
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Article
Open AccessNeferine inhibits BMECs pyroptosis and maintains blood–brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α
Blood–brain barrier disruption is a critical pathological event in the progression of ischemic stroke (IS). Most studies regarding the therapeutic potential of neferine (Nef) on IS have focused on neuroprotect...
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Article
Enhancing electrocatalytic reduction of CO2 to C2+ products with high efficiency at Cu0/Cuδ+ interfaces via iodine modification strategy
Electrocatalytic CO2 reduction reaction (CO2RR) to produce multicarbon (C2+) products over Cu-based catalysts represents an ideal approach for renewable energy storage and carbon emissions reduction. The Cu0/Cuδ+
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Article
Open AccessCholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...
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Article
Open AccessOrganic fertilization co-selects genetically linked antibiotic and metal(loid) resistance genes in global soil microbiome
Antibiotic resistance genes (ARGs) and metal(loid) resistance genes (MRGs) coexist in organic fertilized agroecosystems based on their correlations in abundance, yet evidence for the genetic linkage of ARG-MRG...
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Article
Open AccessAssociation analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson’s disease
Cognitive impairment is a common non-motor symptom of Parkinson’s disease (PD). The apolipoprotein E (APOE) ε4 genotype increases the risk of Alzheimer’s disease (AD). However, the effect of APOEε4 on cognitiv...
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Article
Property evolution and service life prediction of novel metallic materials for future lunar bases
While lunar bases have been a focus of development in recent years, the complex and extreme environment of the lunar surface remains a considerable challenge for lunar exploration. Unlike those on Earth, lunar...
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Article
A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects
FAK (focal adhesion kinase) is widely involved in cancer growth and drug resistance development. Thus, FAK inhibition has emerged as an effective strategy for tumor treatment both as a monotherapy or in combin...
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Article
Novel Polymer-Free Antimicrobial System Based on Octyl Gallate/Hydroxypropyl-β-Cyclodextrin Inclusion Complex Electrospun Nanofibers for Chinese Giant Salamander Preservation
Octyl gallate (GAC8) as a bioactive compound has excellent antibacterial effectiveness, but its poor hydrophilicity limits its applications. In this work, GAC8 was encapsulated into hydroxypropyl-β-cyclodextrin (...
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Article
Timp1 Deletion Induces Anxiety-like Behavior in Mice
The hippocampus is essential for learning and memory, but it also plays an important role in regulating emotional behavior, as hippocampal excitability and plasticity affect anxiety and fear. Brain synaptic pl...
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Article
The First Genome-Wide Survey of Shortbelly Eel (Dysomma anguillare Barnard, 1923) to Provide Genomic Characteristics, Microsatellite Markers and Complete Mitogenome Information
Dysomma anguillare is a demersal eel widespread distributing in tropical waters of the Indo-West Pacific and Atlantic. As an important component of the coastal fishery and marine ecosystem, the lack of genomic in...
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Article
Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Article
Open AccessTranscriptome analysis of Gossypium hirsutum cultivar Zhongzhimian No.2 uncovers the gene regulatory networks involved in defense against Verticillium dahliae
Cotton is globally important crop. Verticillium wilt (VW), caused by Verticillium dahliae, is the most destructive disease in cotton, reducing yield and fiber quality by over 50% of cotton acreage. Breeding resis...
