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Article
Construction of pitch-derived porous carbon-functionalized electrochemical aptasensor for sensitivity detection of chloramphenicol
Chloramphenicol (CAP) is widely used in human and veterinary medicine but has a harmful side effect on human/animal health and ecological risks. The current methods for the detection of CAP are commonly expens...
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Article
Open AccessiIMPACT: integrating image and molecular profiles for spatial transcriptomics analysis
Current clustering analysis of spatial transcriptomics data primarily relies on molecular information and fails to fully exploit the morphological features present in histology images, leading to compromised a...
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Article
Open AccessDeficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer
Several studies have demonstrated a strong correlation between impaired Succinate dehydrogenase (SDH) function and the advancement of tumors. As a subunit of SDH, succinate dehydrogenase complex subunit C (SDH...
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Article
Synthesis and antiviral property of polysulfate-grafted maleimide-based enediynes
Human coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pose a serious threat to human life and the global economy. To combat emerging viruses and virus variants, it is...
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Article
Kinect-based objective assessment of the acute levodopa challenge test in parkinsonism: a feasibility study
The acute levodopa challenge test (ALCT) is an important and valuable examination but there are still some shortcomings with it. We aimed to objectively assess ALCT based on a depth camera and filter out the b...
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Article
Academic atmosphere and graduate students’ innovation ability: the role of scientific research self-efficacy and scientific engagement
At present, our society is more and more interested in innovation ability. The Chinese government emphasizes higher education institutions’ role in forming and develo** students’ innovation abilities. Howeve...
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Article
Evidence for d-wave superconductivity of infinite-layer nickelates from low-energy electrodynamics
The discovery of superconductivity in infinite-layer nickelates established another category of unconventional superconductors that shares structural and electronic similarities with cuprates. However, key iss...
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Article
Nanomaterials Derived from Metal–Organic Frameworks and Their Applications for Pollutants Removal
As a sort of porous material with periodic network structure, metal–organic framework (MOF) is constructed with metal ions or clusters and organic ligands. Benefiting from the adjustable channel structure, abu...
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Article
The evolution of preexisting primary immune thrombocytopenia after COVID-19 onset: A nationally representative, prospective, multicentre, observational study
The symptoms in patients with primary immune thrombocytopenia (ITP) after COVID-19 onset remain largely unclear. The aim of this study was to describe the platelet count fluctuations in ITP patients following ...
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Article
Understanding the 2022 Extreme Dragon-Boat Rainfall in South China from the Combined Land and Oceanic Forcing
The most frequent and concentrated rainfall in the pre-flood season in South China usually occurs around the Dragon Boat Festival every year, locally known as ‘Dragon-boat Rainfall (DBR)’. In 2022, a record-br...
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Article
MVTr: multi-feature voxel transformer for 3D object detection
Convolutional neural networks have become a powerful tool for partial 3D object detection. However, their power has not been fully realized for focusing on global information, which is crucial for object detec...
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Article
Open AccessThe electrode strategy and its coordination mechanism in constructed wetland-microbial fuel cell (CW-MFC): a review
The electrode played an essential role in the operation of CW-MFC system due to its synergistic effect, and the development of electrode strategy has promoted the application of CW-MFC since 2012. In this pape...
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Article
Spatial–temporal redundancy evaluation of the municipal solid waste incineration treatment capacity: the case study of China
In the process of marketization, the lack of redundancy evaluation of the MSW incineration treatment capacity leads to the regional imbalance of treatment capacity and waste of resources. Therefore, this study...
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Article
Open AccessTargeting TIGIT for cancer immunotherapy: recent advances and future directions
As a newly identified checkpoint, T cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif (ITIM) domain (TIGIT) is highly expressed on CD4+ T cells, CD8+ T cells, natural killer (NK) cells, ...
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Article
Open AccessStronger stimulus triggers synaptic transmission faster through earlier started action potential
Synaptic transmission plays an important and time-sensitive role in the nervous system. Although the amplitude of neurotransmission is positively related to the intensity of external stimulus, whether stronger...
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Article
Preparation of nano-zirconium phosphate by freeze-drying method and its tribological properties
In order to explore the influence of freeze-drying process parameters on the size of zirconium phosphate (α-ZrP) nanoparticles during freeze-drying, different process parameters were selected and orthogonal ex...
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Article
Open AccessEnterogenic Stenotrophomonas maltophilia migrates to the mammary gland to induce mastitis by activating the calcium-ROS-AMPK-mTOR-autophagy pathway
Mastitis is an inflammatory disease of the mammary gland that has serious economic impacts on the dairy industry and endangers food safety. Our previous study found that the body has a gut/rumen-mammary gland ...
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Article
Open AccessThe anticancer mechanisms of exopolysaccharide from Weissella cibaria D-2 on colorectal cancer via apoptosis induction
Exopolysaccharide (EPS) from Weissella cibaria has been devoted to the study of food industry. However, the anticancer activity of W. cibaria derived EPS has not yet been investigated. In this study, we obtained ...
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Article
Open AccessExploration on the scientific rationality of low-carbon investment projects from the perspective of supply chain: a case study of CS thermal power plant
Climate warming has gradually become a major problem threatening human survival, and countries have begun to pay attention to carbon emissions. Energy conservation and emission reduction has become a central t...
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Article
Open AccessTumor-associated macrophages confer colorectal cancer 5-fluorouracil resistance by promoting MRP1 membrane translocation via an intercellular CXCL17/CXCL22–CCR4–ATF6–GRP78 axis
Chemotherapy represents a major type of clinical treatment against colorectal cancer (CRC). Aberrant drug efflux mediated by transporters acts as a key approach for tumor cells to acquire chemotherapy resistan...
