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    S6K1 blockade overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer

    The development of resistance to EGFR Tyrosine kinase inhibitors (TKIs) in NSCLC with activating EGFR mutations is a critical limitation of this therapy. In addition to genetic alterations such as EGFR seconda...

    Hua Shen, Gao-Chan Wang, **ang Li, **n Ge, Meng Wang, Zhu-Mei Shi… in Oncogene (2020)