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Nanoparticle (NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-κB pathway and suppress breast cancer growth and metastasis

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  1. Article

    Open Access

    Genomic and phenotypic analysis of a novel clinical isolate of Corynebacterium pyruviciproducens

    Corynebacterium pyruviciproducens is a recently described species of Corynebacterium. There are few reports on the microbiological characteristics of the new species, and there is a lack of reports on the genomic...

    Jiaqi Wang, Jiajia Feng, Wei Jia, Tingxun Yuan, **nyu He, Qianqian Wu in BMC Microbiology (2023)

  2. Article

    Open Access

    The energy metabolism of Balantidium polyvacuolum inhabiting the hindgut of Xenocypris davidi

    Anaerobic parasitic ciliates are a specialized group of ciliates that are adapted to anoxic and oxygen-depleted habitats. Among them, Balantidium polyvacuolum, which inhabits the hindgut of Xenocyprinae fishes, h...

    **a-lian Bu, Wei-shan Zhao, Zhong-yang Li, Hong-wei Ma, Yu-shun Chen in BMC Genomics (2023)

  3. Article

    Open Access

    miR-30e-5p-mediated FOXD1 promotes cell proliferation by blocking cellular senescence and apoptosis through p21/CDK2/Rb signaling in head and neck carcinoma

    Forkhead box D1 (FOXD1) belongs to the FOX protein family, which has been found to function as a oncogene in multiple cancer types, but its role in head and neck squamous cell carcinoma (HNSCC) requires furthe...

    Tong Wu, Zhongyuan Yang, Weichao Chen, Mingjie Jiang, Zhichao **ao in Cell Death Discovery (2023)

  4. Article

    Open Access

    TMT-based proteomic analysis of liquorice root in response to drought stress

    Drought stress is a serious threat to land use efficiency and crop yields worldwide. Understanding the mechanisms that plants use to withstand drought stress will help breeders to develop drought-tolerant medi...

    Dong Zhang, Zhongren Yang, **aoqing Song, Fenglan Zhang, Yan Liu in BMC Genomics (2022)

  5. Article

    Open Access

    Med23 supports angiogenesis and maintains vascular integrity through negative regulation of angiopoietin2 expression

    The mammalian Mediator complex consists of over 30 subunits and functions as a transcriptional hub integrating signaling for tissue-specific gene expression. Although the role of the Mediator complex in transc...

    Yenan Yang, Qi **ao, **gwen Yin, Chonghui Li, Decai Yu in Communications Biology (2022)

  6. Article

    Open Access

    Antibiotic resistance genes in gut of breast-fed neonates born by caesarean section originate from breast milk and hospital ward air

    The human gut is a reservoir of antibiotic resistance genes (ARGs). Even in the absence of antibiotics, ARGs are present in large quantities in faeces of adults, children and even newborns. However, where and ...

    Kunming Zhang, Min **, Dong Yang, Zhiqiang Shen, Weili Liu, **g Yin in BMC Microbiology (2022)

  7. Article

    Open Access

    Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy

    Endothelial-to-mesenchymal transition (EndMT) has been shown to contribute to cardiac fibrosis and heart failure (HF). Recent studies have demonstrated that EndMT is regulated by autophagy, and we previously s...

    Lu Zhang, Jiaqi He, Junyan Wang, **g Liu, Zixin Chen, Bo Deng in Cell Death & Disease (2021)

  8. Article

    Open Access

    PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor

    Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment failure. Lymphangiogenesis is a crucial step in lymp...

    Chuanghua Luo, Haofan Yin, Tianxiao Gao, Caiqi Ma, Junxi Liu in Cell Death & Disease (2021)

  9. Article

    Open Access

    Genome-wide identification, characterization, and expression analysis of the NAC transcription factor family in orchardgrass (Dactylis glomerata L.)

    Orchardgrass (Dactylis glomerata L.) is one of the most important cool-season perennial forage grasses that is widely cultivated in the world and is highly tolerant to stressful conditions. However, little is kno...

    Zhongfu Yang, Gang Nie, Guangyan Feng, Jiating Han, Linkai Huang in BMC Genomics (2021)

  10. Article

    Open Access

    Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

    Chronic heart failure (CHF) is the final outcome of many cardiovascular diseases, and is a severe health issue faced by the elderly population. Mixed lineage kinase 3 (MLK3), a member of MAP3K family, is assoc...

    Junyan Wang, Bo Deng, Qing Liu, Yusheng Huang, Weitao Chen, **g Li in Cell Death & Disease (2020)

  11. Article

    Open Access

    The contrary intracellular and extracellular functions of PEDF in HCC development

    Pigment epithelium-derived factor (PEDF), a classic angiogenic inhibitor, has been reported to function as a tumor suppression protein and to downregulate in many types of solid tumors. However, the expression...

    Cen Li, Zhijian Huang, Liuqing Zhu, **anhuan Yu, Tianxiao Gao in Cell Death & Disease (2019)

  12. Article

    Open Access

    Construction and analysis of degradome-dependent microRNA regulatory networks in soybean

    Usually the microRNA (miRNA)-mediated gene regulatory network (GRN) is constructed from the investigation of miRNA expression profiling and target predictions. However, the higher/lower expression level of miR...

    Rui Wang, Zhongyi Yang, Yuhan Fei, Jiejie Feng, Hui Zhu, Fang Huang in BMC Genomics (2019)

  13. Article

    Open Access

    TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathway

    Thyroid cancer is commonly seen in the clinic with a rapidly increasing incidence globally. COX-2 overexpression correlates with the pathologic type of thyroid carcinoma, and it has been suggested that COX-2 o...

    **aoyan Fu, Huayong Zhang, Zhipeng Chen, Zhongyuan Yang, Dingbo Shi in Cell Death & Disease (2019)

  14. Article

    Open Access

    Integration of small RNAs and transcriptome sequencing uncovers a complex regulatory network during vernalization and heading stages of orchardgrass (Dactylis glomerata L.)

    Flowering is a critical reproductive process in higher plants. Timing of optimal flowering depends upon the coordination among seasonal environmental cues. For cool season grasses, such as Dactylis glomerata, ver...

    Guangyan Feng, Lei Xu, Jian** Wang, Gang Nie, Bradley Shaun Bushman in BMC Genomics (2018)

  15. Article

    Publisher Correction: NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming

    In the version of this Article originally published, in Fig. 2c, the ‘+’ sign and ‘OSKM’ were superimposed in the label ‘+OSKM’. In Fig. 4e, in the labels, all instances of ‘Ant’ should have been ‘Anti-’. And,...

    Qiang Zhuang, Wenjuan Li, Christina Benda, Zhijian Huang in Nature Cell Biology (2018)

  16. Article

    Open Access

    Correction: Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis

    The PDF and HTML versions of the article have been updated to include the Creative Commons Attribution 4.0 International License information.Correction to: Cell Death Dis. 5, e1484 (2014); https:...

    Ting Zhang, ** Yin, Zichen Zhang, Banglao Xu, Di Che, Zhiyu Dai in Cell Death & Disease (2018)

  17. Article

    Genome sequencing and phylogenetic analysis of Banna virus (genus Seadornavirus, family Reoviridae) isolated from Culicoides

    In an investigation of blood-sucking insects and arboviruses, a virus (YN12243) was isolated from Culicoides samples collected in the Sino-Burmese border region of Yunnan Province, China. The virus caused cyto...

    Song Song, Yuanyuan Li, Shihong Fu, Wenwen Lei, **aofang Guo in Science China Life Sciences (2017)

  18. Article

    Open Access

    Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis

    Distant metastasis is the primary cause of nasopharyngeal carcinoma (NPC) treatment failure while epithelial–mesenchymal transition (EMT) is the critical process of NPC invasion and metastasis. However, tumor-...

    Ting Zhang, ** Yin, Zichen Zhang, Banglao Xu, Di Che, Zhiyu Dai in Cell Death & Disease (2017)

  19. Article

    Open Access

    A retrospective study of the occurrence of ischemic-type biliary lesions post liver transplantation

    Rui Shi, Ya-Min Zhang, Yong-Lin Deng, Hong Zheng, Cheng Pan in Science China Life Sciences (2016)

  20. Article

    Open Access

    Proteomics of methyl jasmonate induced defense response in maize leaves against Asian corn borer

    Jasmonic acid (JA) and methyl jasmonate (MeJA) regulate plant development, resistance to stress, and insect attack by inducing specific gene expression. However, little is known about the mechanism of plant de...

    Yi Tong Zhang, Yu Liang Zhang, Si Xue Chen, Guo Hua Yin, Ze Zhong Yang in BMC Genomics (2015)

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