Skip to main content

8 Result(s)

within Zhiya Yu Remove this filter Biomedicine, general Remove this filter

and

  1. No Access

    Article

    The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity

    Stem cells are maintained by transcriptional programs that promote self-renewal and repress differentiation. Here, we found that the transcription factor c-Myb was essential for generating and maintaining stem...

    Sanjivan Gautam, Jessica Fioravanti, Wei Zhu, John B. Le Gall… in Nature Immunology (2019)

  2. Article

    Open Access

    Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

    David Carbone, Michael Sharpnack, Kai He… in Journal of Translational Medicine (2018)

    Download PDF (1027 KB) View Article

  3. Article

    Open Access

    Immunotherapy Bridge 2016 and Melanoma Bridge 2016: meeting abstracts

    Vera Hirsh, Sandro Pignata, Melissa Bersanelli… in Journal of Translational Medicine (2017)

    Download PDF (799 KB) View Article

  4. Article

    BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers

    T cell activation upon TCR signaling can lead to development of effector and memory cells. Roychoudhuri and colleagues show that the transcription factor BACH2 promotes memory CD8+ T cell generation by blocking a...

    Rahul Roychoudhuri, David Clever, Peng Li, Yoshiyuki Wakabayashi… in Nature Immunology (2016)

    Download PDF (1850 KB) View Article

  5. Article

    Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells

    The molecular basis of CD8+ memory is still being delineated. Gattinoni et al. show that the DNA-binding inhibitor Id3 is critical for the formation of long-lived memory.

    Yun Ji, Zoltan Pos, Mahadev Rao, Christopher A Klebanoff, Zhiya Yu… in Nature Immunology (2011)

    Download PDF (1536 KB) View Article

  6. Article

    Open Access

    Permissivity of the NCI-60 cancer cell lines to oncolytic Vaccinia Virus GLV-1h68

    Oncolytic viral therapy represents an alternative therapeutic strategy for the treatment of cancer. We previously described GLV-1h68, a modified Vaccinia Virus with exclusive tropism for tumor cells, and we ob...

    Maria Libera Ascierto, Andrea Worschech, Zhiya Yu, Sharon Adams… in BMC Cancer (2011)

    Download PDF (2398 KB) View Article

  7. No Access

    Article

    A human memory T cell subset with stem cell–like properties

    Whether there exists a human memory T cell population with stem cell–like properties of self-renewal and multipotency is under active investigation. Here Gattinoni et al. characterize a subset of human T cells th...

    Luca Gattinoni, Enrico Lugli, Yun Ji, Zoltan Pos, Chrystal M Paulos… in Nature Medicine (2011)

  8. Article

    Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

    The Wnt pathway has a central role in stem cell regulation. Gattinoni et al. now show that activation of the Wnt signaling cascade in naive CD8+ T cells blocks their differentiation into effector T cells and trig...

    Luca Gattinoni, **ao-Song Zhong, Douglas C Palmer, Yun Ji… in Nature Medicine (2009)

    Download PDF (859 KB) View Article