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Article
Open AccessAssociation between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation
The objective of this study was to investigate the relationship between P2Y1 and P2Y12 genotypes and the risk of acute myocardial infarction (AMI) in the Quanzhou population and to determine associations betwe...
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Article
H3K4 demethylase KDM5B regulates cancer cell identity and epigenetic plasticity
The H3K4 demethylase KDM5B is overexpressed in multiple cancer types, and elevated expression levels of KDM5B is associated with decreased survival. However, the underlying mechanistic contribution of dysregul...
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Article
Open AccessPsychopathological symptom network structure in transgender and gender queer youth reporting parental psychological abuse: a network analysis
This is the first study to investigate the effect of parental psychological abuse on potential psychopathological symptoms in gender minority youth subgroups, including transgender women, transgender men, and ...
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Article
Open AccessChanges in network centrality of psychopathology symptoms between the COVID-19 outbreak and after peak
The current study investigated the mechanism and changes in psychopathology symptoms throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and the afte...
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Article
Open AccessHigh-dose N-acetylcysteine for long-term, regular treatment of early-stage chronic obstructive pulmonary disease (GOLD I–II): study protocol for a multicenter, double-blinded, parallel-group, randomized controlled trial in China
The presence of increased oxidative stress and airway inflammation has been proven in subjects with chronic obstructive pulmonary disease (COPD). Several studies have demonstrated that drugs with antioxidant a...
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Article
Open AccessMap** out a spectrum of the Chinese public’s discrimination toward the LGBT community: results from a national survey
China has the world’s largest lesbian, gay, bisexual, and transgender (LGBT) population. This study assessed the discrimination experienced by LGBT individuals in China in a comprehensive way, covering discrim...
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Article
Open AccessAn exploratory model for the non-fatal drowning risks in children in Guangdong, China
Drowning is a leading cause of accidental death in children under 14 years of age in Guangdong, China. We developed a statistical model to classify the risk of drowning among children based on the risk factors.
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Article
Open AccessQuality of randomized controlled trials reporting in the treatment of melasma conducted in China
There is no existing report on the quality of randomized controlled trials (RCTs) of melasma treatment currently conducted in China. This study aims to assess the quality of RCT- reporting in the treatment of ...
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Article
Open AccessCannulated Screw and Cable are Superior to Modified Tension Band in the Treatment of Transverse Patella Fractures
Although the modified tension band technique (eg, tension band supplemented by longitudinal Kirschner wires) has long been the mainstay for fixation of transverse fractures of the patella, it has shortcomings,...