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Early initiation of ARBs without blood pressure risk via neutrophil membrane-fused pH-sensitive liposomes to reduce cardiomyocyte apoptosis after acute myocardial infarction
Activation of the local renin–angiotensin system (RAS) promotes cardiomyocyte apoptosis and cardiac remodeling after acute myocardial infarction (AMI). As an anti-RAS drug, the effect of Valsartan in the early...
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Versatile nanocomposite augments high-intensity focused ultrasound for high-efficacy sonodynamic therapy of glioma
High-intensity focused ultrasound (HIFU), with inherent advantages of improved ultrasonic depth and low off-target damage, holds the promising capability for glioma treatment, but the relatively long therapeut...
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Tumor Microenvironment and Intracellular Signal-Activated Nanocomposites for Anticancer Drug Delivery
The use of nanomaterials for drug delivery and cancer therapy has well established itself over the past decades. Compared with free chemotherapeutics, nanoparticle drug delivery systems achieve better performa...
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Drug targeting through platelet membrane-coated nanoparticles for the treatment of rheumatoid arthritis
The effective drug treatment of rheumatoid arthritis (RA) is hindered by poor delivery efficiency to the diseased site and the serious side effects caused by wide-spread drug distribution. Traditional drug-tar...