23 Result(s)
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Article
Induction of apoptosis and change of bcl-2 expression in macrophage Ana-1 cells by all-trans retinoic acid
Macrophage cells play an important role in the initiation and regulation of the immune response. All-trans retinoic acid (ATRA) and its natural and synthetic analogs (retinoids) affect a large number of biolog...
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Article
Studies on DNA-protein interactions in the upstream regulatory region of the human ɛ-globin gene promoter
The erythroid- and developmental stage-specific expression of the human ɛ-globin gene is controlled, in part, by the 5′-flanking DNA sequence of this gene. In the present study, we have used DNA-protein bindin...
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Article
Trans-acting factors from the human fetal liver binding to the human ɛ-globin gene silencer
The developmental stage-specific silencing of the human ɛ-globin gene during embryonic life is controlled, in part, by the silencer (−392bp ∼ −177bp) upstream of this gene. In order to elucidate its role, the nuc...
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Visualization of chromatin folding patterns in chicken erythrocytes by atomic force microscopy (AFM)
The organization of the higher order structure of chromatin in chicken erythrocytes has been examined with tap**-mode scanning force microscopy under conditions close to their native environment. Reproducibl...
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Article
The 5′-flanking cis-acting elements of the human ɛ-globin gene associates with the nuclear matrix and binds to the nuclear matrix proteins
The nuclear matrix attachment regions(MARs) and the binding nuclear matrix proteins in the 5′-flanking cis acting elements of the human ɛ-globin gene have been examined. Using in vitro DNA-matrix binding assay...
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Article
Genomewide analysis indicates that queen larvae have lower methylation levels in the honey bee (Apis mellifera)
The honey bee is a social insect characterized by caste differentiation, by which a young larva can develop into either a queen or a worker. Despite possessing the same genome, queen and workers display marked...
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Open AccessIncreased leptin by hypoxic-preconditioning promotes autophagy of mesenchymal stem cells and protects them from apoptosis
Autophagy is the basic catabolic progress involved in cell degradation of unnecessary or dysfunctional cellular components. It has been proven that autophagy could be utilized for cell survival under stresses....
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Open AccessGenome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs
Age-related physiological, biochemical and functional changes in mammalian skeletal muscle have been shown to begin at the mid-point of the lifespan. However, the underlying changes in DNA methylation that occ...
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Open AccessTranscriptome differences in the hypopharyngeal gland between Western Honeybees (Apis mellifera) and Eastern Honeybees (Apis cerana)
Apis mellifera and Apis cerana are two sibling species of Apidae. Apis cerana is adept at collecting sporadic nectar in mountain and forest region and exhibits stiffer hardiness and acarid resistance as a result ...
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Article
Nutrition affects longevity and gene expression in honey bee (Apis mellifera) workers
Nutrition is a major factor affecting animal health, resistance to disease, and survival. In honey bees (Apis mellifera), nectar or honey (carbohydrates) is the energy source, while pollen, which is the sole diet...
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Article
Open AccessDe novo assembly of soybean wild relatives for pan-genome analysis of diversity and agronomic traits
Sequencing and de novo assembly of seven wild relatives of soybean yields insights relevant to crop domestication and improvement.
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Article
Differentially expressed microRNAs between queen and worker larvae of the honey bee (Apis mellifera)
Although the honey bee queen and worker have identical genomes, they exhibit morphological, behavioral, and reproductive differences. Queen larvae (QL) and worker larvae (WL) have different gene and protein ex...
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Article
Open AccessSequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement
Two draft sequences of Gossypium hirsutum, the most widely cultivated cotton species, provide insights into genome structure, genome rearrangement, gene evolution and cotton fiber biology.
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Article
Open AccessScallop genome provides insights into evolution of bilaterian karyotype and development
Reconstructing the genomes of bilaterian ancestors is central to our understanding of animal evolution, where knowledge from ancient and/or slow-evolving bilaterian lineages is critical. Here we report a high-...
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Open AccessA genome for gnetophytes and early evolution of seed plants
Gnetophytes are an enigmatic gymnosperm lineage comprising three genera, Gnetum, Welwitschia and Ephedra, which are morphologically distinct from all other seed plants. Their distinctiveness has triggered much de...
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Article
Open AccessLeptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation
Accumulating evidence revealed that mesenchymal stem cells (MSCs) confer cardioprotection against myocardial infarction (MI). However, the poor survival and engraftment rate of the transplanted cells limited t...
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Article
The cap** pheromones and putative biosynthetic pathways in worker and drone larvae of honey bees Apis mellifera
In honey bees (Apis mellifera), methyl palmitate (MP), methyl oleate (MO), methyl linoleate (ML), and methyl linolenate (MLN) are important pheromone components of the cap** pheromones triggering the cap** be...
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Article
Effects of commercial queen rearing methods on queen fecundity and genome methylation
The queen and worker castes of the honey bee are very distinct phenotypes that result from different epigenomically regulated developmental programs. In commercial queen rearing, it is common to produce queens...
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Open AccessFemale developmental environment delays development of male honeybee (Apis mellifera)
Nutrition and cell size play an important role in the determination of caste differentiation in queen and worker of honeybees (Apis mellifera), whereas the haploid genome dominates the differentiation of drones. ...
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Article
The involvement of a floral scent in plant-honeybee interaction
Volatile odors from flowers play an important role in plant-pollinator interaction. The honeybee is an important generalist pollinator of many plants. Here, we explored whether any components of the odors of a...
