63 Result(s)

Article

A radiomics signature derived from CT imaging to predict MSI status and immunotherapy outcomes in gastric cancer: a multi-cohort study

Accurate microsatellite instability (MSI) testing is essential for identifying gastric cancer (GC) patients eligible for immunotherapy. We aimed to develop and validate a CT-based radiomics signature to predic...

Peng-chao Zhan, Shuo Yang, **ng Liu, Yu-yuan Zhang, Rui Wang, Jia-xing Wang… in BMC Cancer (2024)

Article

Dynamic single-cell map** unveils Epstein‒Barr virus-imprinted T-cell exhaustion and on-treatment response

Epstein‒Barr virus (EBV)-associated gastric cancer (GC) manifests an intriguing immunotherapy response. However, the cellular basis for EBV-imprinted tumour immunity and on-treatment response remains undefined...

Miao-Zhen Qiu, Chaoye Wang, Zhiying Wu, Qi Zhao… in Signal Transduction and Targeted Therapy (2023)

Article

High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals. However, HDL from patients with coronary artery disease undergoes various modifications, becomes dysfunctional (dHDL), and...

Zhi-Wei Mo, Yue-Ming Peng, Yi-**n Zhang, Yan Li… in Signal Transduction and Targeted Therapy (2023)

Article

Erratum to: Tetrandrine Represses Inflammation and Attenuates Osteoarthritis by Selective Inhibition of COX-2

The authors examined the original data of their work and noticed misuse of images in fig. 1 and fig. 3 (as shown below on the upper panels, red box). The correct images are shown on the lower panels (red box)....

** Gao, Zhi-wei Rao, Min Li, Xu-ying Sun, Qian-yan Gao… in Current Medical Science (2023)

Article

Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors

The comorbidity of autism spectrum disorder and anxiety is common, but the underlying circuitry is poorly understood. Here, Tmem74^-/- mice showed autism- and anxiety-like behaviors along with increased excitabili...

Yi-Fan Luo, Lu Lu, Heng-Yi Song, Han Xu, Zhi-Wei Zheng, Zhou-Yue Wu… in Molecular Psychiatry (2023)

Article

The SMARCA4^R1157W mutation facilitates chromatin remodeling and confers PRMT1/SMARCA4 inhibitors sensitivity in colorectal cancer

Genomic studies have demonstrated a high frequency of genetic alterations in components of the SWI/SNF complex including the core subunit SMARCA4. However, the mechanisms of tumorigenesis driven by SMARCA4 mut...

**angwei Zeng, Bing Yao, Jianpeng Liu, Guan-Wen Gong, Ming Liu… in npj Precision Oncology (2023)

Article

Retraction Note: LINC01410-miR-532-NCF2-NF-kB feedback loop promotes gastric cancer angiogenesis and metastasis

Jia-**ng Zhang, Zhen-Hua Chen, Dong-Liang Chen, **ao-Peng Tian, Chen-Yuan Wang… in Oncogene (2023)

Article

Noninvasive prediction of axillary lymph node status in breast cancer using promoter profiling of circulating cell-free DNA

Lymph node metastasis (LNM) is one of the most important factors affecting the prognosis of breast cancer. The accurate evaluation of lymph node status is useful to predict the outcomes of patients and guide t...

Zhi-Wei Guo, Qing Liu, Xu Yang, Geng-** Cai… in Journal of Translational Medicine (2022)

Article

Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

Both Response Evaluation Criteria in Solid Tumors (RECIST) and tumor regression grade (TRG) play key roles in evaluating tumor response. We analyzed the consistency of TRG and RECIST 1.1 for gastric cancer (GC...

Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu… in BMC Cancer (2022)

Article

BOD1 regulates the cerebellar IV/V lobe-fastigial nucleus circuit associated with motor coordination

Cerebellar ataxias are characterized by a progressive decline in motor coordination, but the specific output circuits and underlying pathological mechanism remain poorly understood. Through cell-type-specific ...

**u-**u Liu, **ng-Hui Chen, Zhi-Wei Zheng… in Signal Transduction and Targeted Therapy (2022)

Article

Radiomics combined with clinical characteristics predicted the progression-free survival time in first-line targeted therapy for advanced non-small cell lung cancer with EGFR mutation

This study was to explore the most appropriate radiomics modeling method to predict the progression-free survival of EGFR-TKI treatment in advanced non-small cell lung cancer with EGFR mutations. Different mac...

Jian-man Zhu, Lei Sun, Lin**g Wang, Tong-Chong Zhou, Yawei Yuan… in BMC Research Notes (2022)

Article

Efficacy and safety of long-term transcutaneous electroacupuncture versus sham transcutaneous electroacupuncture for delayed gastric emptying after distal gastrectomy: study protocol for a randomized, patient-assessor blinded, controlled trial

Delayed gastric emptying (DGE) after distal gastrectomy impacts patients’ nutritional status and quality of life. The current treatments of DGE seem unsatisfactory or need invasive interventions. It is unknown...

Kai-Bo Chen, Zhi-Wei Wu, Jun Wang, Ling-Hua Zhu, **ao-Li **, Guo-Feng Chen… in Trials (2022)

Article

Optimal Formula of Angelica sinensis Ameliorates Memory Deficits in β-amyloid Protein-induced Alzheimer’s Disease Rat Model

Angelica (A.) sinensis is used as a traditional medical herb for the treatment of neurodegeneration, aging, and inflammation in Asia. A. sinensis optimal formula (AOF) is the best combination in A. sinensis that ...

Hu-** Wang, Hong-yan Wu, Chun-lin Ma, Qing-tao Zeng… in Current Medical Science (2022)

Article

Correction to: PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

Bing Yao, Tao Gui, **angwei Zeng, Yexuan Deng, Zhi Wang, Ying Wang… in Genome Medicine (2021)

Article

The association between plasma furin and cardiovascular events after acute myocardial infarction

Furin is the key enzyme involved in the cleavage of pro-BNP and plays a critical role in the cardiovascular system through its involvement in lipid metabolism, blood pressure regulation and the formation of at...

Zhi-Wei Liu, Qiang Ma, Jie Liu, **g-Wei Li, Yun-Dai Chen in BMC Cardiovascular Disorders (2021)

Article

LINC00852 promotes the proliferation and invasion of ovarian cancer cells by competitively binding with miR-140-3p to regulate AGTR1 expression

Dysregulation of long non-coding RNAs (lncRNAs) has been identified in ovarian cancer. However, the expression and biological functions of LINC00852 in ovarian cancer are not understood.

Zhi-wei Qiao, Ying Jiang, Ling Wang, Lei Wang, **g Jiang, **g-ru Zhang… in BMC Cancer (2021)