299 Result(s)
within
English
Internal Medicine
Zhi-**a Yang
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Article
Peroxisome proliferator-activated receptor γ ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines
To study the effect of peroxisome proliferator-actived receptor γ (PPARγ) ligands on cell proliferation and apoptosis in human renal carcinoma cell lines.
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Relationship between leukocyte count and angiographical characteristics of coronary atherosclerosis
To explore the relationship between differential leucocyte count and coronary atherosclerosis.
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Article
Identification of human dopamine D1-like receptor agonist using a cell-based functional assay
To establish a cell-based assay to screen human dopamine D1 and D5 receptor agonists against compounds from a natural product compound library.
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Article
Distributive characteristics of Ser49Gly and Gly389Arg genetic polymorphisms of β1-adrenoceptor in Chinese Han and Dai populations
Genetic polymorphisms causing Ser49Gly and Gly389Arg mutants of β1- adrenoceptor may result in significant changes in the function of this receptor. The aim of the present study was to investigate the frequencies...
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Article
Electrophysiological effect of fluoxetine on Xenopus oocytes heterologously expressing human serotonin transporter
To investigate the electrophysiological effect of fluoxetine on serotonin transporter.
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Article
Multiple dose pharmacokinetics of risperidone and 9-hydroxyrisperidone in Chinese female patients with schizophrenia
To study the multiple dose clinical pharmacokinetics of risperidone and its main active metabolite, 9-hydroxyrisperidone, in Chinese female patients with schizophrenia.
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Article
Induction of collateral artery growth and improvement of post-infarct heart function by hepatocyte growth factor gene transfer
To study the effect of adenovirus5-mediated human hepatocyte growth factor (Ad5-HGF) transfer on post-infarct heart failure in a swine model.
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Article
Intrathecal administration of Cav3.2 and Cav3.3 antisense oligonucleotide reverses tactile allodynia and thermal hyperalgesia in rats following chronic compression of dorsal root of ganglion
The present study aimed to elucidate the role of T-subtype calcium channels (Cav3.1, Cav3.2, and Cav3.3) in the pathogenesis of neuropathic pain at spinal level.
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Article
Angiotensin-Converting Enzyme Gene 2350 G/A Polymorphism Is Associated with Left Ventricular Hypertrophy but Not Essential Hypertension
The angiotensin-converting enzyme (ACE) gene (ACE) is one of the most studied candidate genes related to essential hypertension (EH) and left ventricular hypertrophy (LVH). ACE rs4343 synonymous coding polymorphi...
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Article
Thrombolytic efficacy of native recombinant staphylokinase on femoral artery thrombus of rabbits
To investigate the thrombolytic efficacy, ideal dosage and administration of native recombinant staphylokinase (r-SAK).
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Article
Serum sodium concentration is significantly associated with the angiographic characteristics of coronary atherosclerosis
To explore the relationship between serum sodium concentration and coronary atherosclerosis.
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Article
Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease
To investigate the relationship between aquaporin-5 (AQP5) expression and mucus overproduction in the airways of Chinese patients with chronic obstructive pulmonary disease (COPD) and the correlation with pulmona...
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Article
Heat shock protein 90 acts as a molecular chaperone in late-phase activation of extracellular signal-regulated kinase 1/2 stimulated by oxidative stress in vascular smooth muscle cells
To investigate whether cytosolic heat shock protein 90 (HSP90) acts as a molecular chaperone on the activated extracellular signal-regulated kinase 1/2 (ERK1/2) and cell proliferation stimulated by reactive ox...
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Article
Possible arrhythmiogenic mechanism produced by ibuprofen
The aim of the present study was to investigate the electrophysiological effect of ibuprofen on the cardiac action potentials (AP) and electrocardiograms (ECG), and to identify its arrhythmiogenic mechanism.
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Article
Synergy of gemcitabine and lidamycin associated with NF-κB downregulation in pancreatic carcinoma cells
To investigate the effects on human pancreatic cancer PANC-1 and SW1990 cells using a combination of lidamycin (LDM) and gemcitabine.
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Article
Association of human carboxypeptidase E exon5 gene polymorphisms with angiographical characteristics of coronary atherosclerosis in a Chinese population
To explore the association between 801C>T and 847C>T polymorphisms of the human carboxypeptidase E (CPE) gene exon5, which could cause hyperproinsulinemia, and the angiographical characteristics of coronary at...
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Article
Ability of alpha-lipoic acid to reverse the diabetic cystopathy in a rat model
The present study was conducted to investigate whether alpha-lipoic acid (α-LA) is able to reverse impaired bladder function induced by diabetes in a rat model and to explore the possible mechanism mediating t...
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Article
Association of serum sodium concentration with coronary atherosclerosis in China: follow-up study
The aim of this study was to test the hypothesis that lower serum sodium may be associated with increased cardiovascular events and all-cause mortality by means of long-term follow-up of subjects with coronary...
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Article
Beta-receptor activation increases sodium current in guinea pig heart
To study the influence of β-receptor activation on sodium channel current and the physiological significance of increased sodium current with regard to the increased cardiac output caused by sympathetic excita...
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Article
An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study
To improve and validate an analytical method based on liquid chromatography and electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) for the quantitative measurement of ilaprazole and its two metabl...
