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Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives

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    Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation

    Stimulator of interferon gene (STING) is increasingly exploited for the potential in cancer immunotherapy, yet its mechanism of activation remains not fully understood. Herein, we designed a novel STING agonis...

    Zuoquan **e, Zhen Wang, Fengying Fan, **pei Zhou, Zhaoxue Hu… in Cell Discovery (2022)

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