40 Result(s)

Article

Comparison of gut transcriptome and bacterial composition of the yellow peach moth, Conogethes punctiferalis larvae associated with host plants adaptation

The yellow peach moth, Conogethes punctiferalis, is one of the most destructive polyphagous pests to corn crops in the Huang-Huai-Hai summer corn region of China. However, little is known about the host plant ada...

Yuqing Gao, Mengqi Ji, Shaohua Li, Saige Wang… in CABI Agriculture and Bioscience (2024)

Article

TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson’s Disease Mice and LPS-Induced BV2 Cells

Microglia-mediated neuroinflammation plays a crucial role in the pathogenesis of Parkinson’s disease (PD). Triggering receptor expressed on myeloid cells 2 (TREM2) confers strong neuroprotective effects in PD ...

Peiting Huang, Zhanyu Zhang, Piao Zhang, Jiezhu Feng, Jianwei **e… in Molecular Neurobiology (2024)

Article

DLD is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients

Since the discovery of copper induces cell death(cuprotosis) in 2022, it has been one of the biggest research hotspots. cuprotosis related genes (CRGs) has been demonstrated to be a potential therapeutic targe...

Can Chen, Dandan Kang, Zhenzhen Chen, Pengfei Shi, Yun Li, Shenxian Qian in Apoptosis (2024)

Article

Human emergency behaviour and psychological stress characteristic mining based on large-scale emergencies

Human emergency behaviour and psychological stress response in emergencies are important scientific issues in basic emergency management research. The analysis of the dynamic characteristics of large-scale hum...

Yi Luo, ** Yang, **aoming Li… in Computational and Mathematical Organizatio… (2024)

Article

Crosstalk between colorectal CSCs and immune cells in tumorigenesis, and strategies for targeting colorectal CSCs

Cancer immunotherapy has emerged as a promising strategy in the treatment of colorectal cancer, and relapse after tumor immunotherapy has attracted increasing attention. Cancer stem cells (CSCs), a small subse...

Qi Zhao, Hong Zong, **** Zhu, Chang Su… in Experimental Hematology & Oncology (2024)

Article

Author Correction: Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4

Zhenzhen Chen, Taylor Lundy, Zhongliang Zhu, Victoria E. Hoskins… in Cell Discovery (2023)

Article

The updates and implications of cutaneous microbiota in acne

Acne is a chronic inflammatory skin disorder that profoundly impacts the quality of life of patients worldwide. While it is predominantly observed in adolescents, it can affect individuals across all age group...

Cong Huang, Fan Zhuo, Baoquan Han, Wenting Li, Bin Jiang… in Cell & Bioscience (2023)

Article

Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4

Zhenzhen Chen, Taylor Lundy, Zhongliang Zhu, Victoria E. Hoskins… in Cell Discovery (2023)

Article

Abnormal cerebellum connectivity patterns related to motor subtypes of Parkinson’s disease

Cerebellar dysfunction may substantially contribute to the clinical symptoms of Parkinson’s disease (PD). The role of cerebellar subregions in tremors and gait disturbances in PD remains unknown. To investigat...

Zhenzhen Chen, Chentao He, Piao Zhang, **n Cai… in Journal of Neural Transmission (2023)

Article

mcPGK1-dependent mitochondrial import of PGK1 promotes metabolic reprogramming and self-renewal of liver TICs

Liver tumour-initiating cells (TICs) contribute to tumour initiation, metastasis, progression and drug resistance. Metabolic reprogramming is a cancer hallmark and plays vital roles in liver tumorigenesis. How...

Zhenzhen Chen, Qiankun He, Tiankun Lu, Jiayi Wu, Gaoli Shi… in Nature Communications (2023)

Article

Nanowarming and ice-free cryopreservation of large sized, intact porcine articular cartilage

Successful organ or tissue long-term preservation would revolutionize biomedicine. Cartilage cryopreservation enables prolonged shelf life of articular cartilage, posing the prospect to broaden the implementat...

Peng Chen, Shang** Wang, Zhenzhen Chen, Pengling Ren… in Communications Biology (2023)

Article

Tumor immune cell infiltration score based model predicts prognosis in multiple myeloma

The tumor microenvironment plays an important role in various processes, including tumorigenesis, cancer progression, and metastasis. Immune signatures have been identified and verified for use in diagnosis an...

Can Chen, Yiwei Li, Peiwen Miao, Ying Xu, Zhenzhen Chen… in Scientific Reports (2022)

Article

Correction: LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation

Zhenzhen Chen, Yanfeng Gao, Lintong Yao, Yating Liu, Lan Huang, Zhongyi Yan… in Oncogene (2022)

Article

Dysfunction of the energy sensor NFE2L1 triggers uncontrollable AMPK signaling and glucose metabolism reprogramming

The antioxidant transcription factor NFE2L1 (also called Nrf1) acts as a core regulator of redox signaling and metabolism homeostasis, and thus, its dysfunction results in multiple systemic metabolic diseases....

Lu Qiu, Qiufang Yang, Wenshan Zhao, Yadi **ng, Peng Li… in Cell Death & Disease (2022)

Article

Correction: MiR-193b-3p–ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes

Cong Huang, Weilong Zhong, Xuanyao Ren, **a Huang, Zizhuo Li… in Cell Death & Disease (2021)

Article

MiR-193b-3p–ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes

Psoriasis is an auto-inflammatory skin disease characterized by abnormal activation of epidermal keratinocytes, aberrant neovascularization, and dysregulation of immune cells. MicroRNAs are small non-coding RN...

Cong Huang, Weilong Zhong, Xuanyao Ren, **a Huang, Zizhuo Li… in Cell Death & Disease (2021)

Article

d-Serine produces antidepressant-like effects in mice through suppression of BDNF signaling pathway and regulation of synaptic adaptations in the nucleus accumbens

d-Serine is a crucial endogenous co-agonist of N-methyl-d-aspartate receptors (NMDARs) in the central nervous system and can affect the function of the brain derived neurotrophic factor (BDNF) system, which plays...

Zhenzhen Chen, Zhenyu Tang, Ke Zou, Zhihong Huang, Liuer Liu… in Molecular Medicine (2021)

Article

Opportunities and challenges of glioma organoids

Glioma is the most common primary brain tumor and its prognosis is poor. Despite surgical removal, glioma is still prone to recurrence because it grows rapidly in the brain, is resistant to chemotherapy, and i...

**angdong Xu, Lingfei Li, Linting Luo, Lingling Shu… in Cell Communication and Signaling (2021)

Article

Amnion signals are essential for mesoderm formation in primates

Embryonic development is largely conserved among mammals. However, certain genes show divergent functions. By generating a transcriptional atlas containing >30,000 cells from post-implantation non-human primat...

Ran Yang, Alexander Goedel, Yu Kang, Chenyang Si, Chu Chu… in Nature Communications (2021)

Article

Correction to: Effect of Surface Property on the Release and Oral Absorption of Solid Sirolimus-Containing Self-Microemulsifying Drug Delivery System

A Correction to this paper has been published: https://doi.org/10.1208/s12249-021-01997-w

Xueting Zhang, Zhenzhen Chen, Chun Tao, **g Zhang, Minxin Zhang… in AAPS PharmSciTech (2021)