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  1. Article

    Open Access

    Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis

    Co-expression of chimeric switch receptors (CSRs) specific for PD-L1 improves the antitumor effects of chimeric antigen receptor (CAR) T cells. However, the effects of trans-recognition between CSRs and PD-L1 ...

    Le Qin, Yuanbin Cui, Tingjie Yuan, Dongmei Chen, Ruocong Zhao in Nature Communications (2022)