19 Result(s)
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Article
Open AccessExtrachromosomal circular DNA (eccDNA): from carcinogenesis to drug resistance
Extrachromosomal circular DNA (eccDNA) is a circular form of DNA that exists outside of the chromosome. Although it has only been a few decades since its discovery, in recent years, it has been found to have a...
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Safety and efficacy of laparoscopic transperitoneal versus retroperitoneal resection for benign retroperitoneal tumors: a retrospective cohort study
Benign retroperitoneal tumors (BRTs) are clinically rare solid tumors. This study aimed to compare the safety and efficacy of laparoscopic transperitoneal versus retroperitoneal resection for BRTs.
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Article
Open AccessIL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis
Previous studies have shown that interleukin-27 (IL-27) can reduce bleomycin (BLM)-induced pulmonary fibrosis (PF). However, the underlying mechanism by which IL-27 attenuates PF is not fully clear.
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Article
Open AccessAssessment of biosafety and implantation feasibility of novel phakic refractive lens
We investigated the biosafety and implantation feasibility of a new phakic refractive lens (PRL) in rabbit eyes.
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Article
Trocar layouts in laparoscopic liver surgery
Since the first laparoscopic wedge resection reported by Reich, laparoscopic liver resection (LLR) has been progressively developed, acquiring safety and feasibility. The time has witnessed a milestone leap fo...
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Article
Open AccessComparison of weight loss induced by daily caloric restriction versus intermittent fasting (DRIFT) in individuals with obesity: study protocol for a 52-week randomized clinical trial
The standard of care for treating overweight and obesity is daily caloric restriction (DCR). While this approach produces modest weight loss, adherence to DCR declines over time and weight regain is common. In...
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Article
Temporal patterns of physical activity in successful weight loss maintainers
Individuals successful at weight loss maintenance engage in high amounts of physical activity (PA). Understanding how and when weight loss maintainers accumulate PA within a day and across the week may inform ...
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Open AccessEffect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China
The effect of the COVID-19 outbreak has led policymakers around the world to attempt transmission control. However, lockdown and shutdown interventions have caused new social problems and designating policy re...
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Clinical characteristics and outcomes of primary adrenal diffuse large B cell lymphoma in a large contemporary cohort: a SEER-based analysis
Primary adrenal lymphoma (PAL) is an extremely rare lymphoma, and the most common histologic type is diffuse large B cell lymphoma (DLBCL). Primary adrenal DLBCL has a quite poor prognosis, but the prognostic ...
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Article
Open AccessClinical features of rabies patients with abnormal sexual behaviors as the presenting manifestations: a case report and literature review
Abnormal sexual behaviors presenting as manifestations of rabies have occasionally been reported in the literature, although little attention has been paid to these cases to date. This study aimed to analyze t...
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Open AccessWeight restoration on a high carbohydrate refeeding diet promotes rapid weight regain and hepatic lipid accumulation in female anorexic rats
There is currently no standard clinical refeeding diet for the treatment of anorexia nervosa (AN). To provide the most efficacious AN clinical care, it is necessary to define the metabolic effects of current r...
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Cross-Links Do Not Improve Clinical or Radiographic Outcomes of Posterior Spinal Fusion With Pedicle Screws in Adolescent Idiopathic Scoliosis: A Multicenter Cohort Study
Retrospective, comparative analysis.
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Article
Open AccessIL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation
Interleukin-27 (IL-27) is a multifunctional cytokine with both pro-inflammatory and immunoregulatory functions. At present, the role of IL-27 in pulmonary fibrosis remains unknown.
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Article
Tachyarrhythmias After the Norwood Procedure: Relationship and Effect of Vasoactive Agents
Tachyarrhythmias are common after the Norwood stage I palliation. The effects of vasoactive medications on the development of post-operative tachyarrhythmias have not been studied. The primary objective was to...
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Article
Results of Treatment of Femoroacetabular Im**ement in Adolescents with a Surgical Hip Dislocation Approach
The literature contains few studies of open treatment with an open surgical hip dislocation approach for treatment of femoroacetabular im**ement (FAI) in adolescents. The average age and associated disorders...
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Article
Esophageal human β-defensin expression in eosinophilic esophagitis
Defensins are antimicrobial peptides expressed on mucosal surfaces that contribute to maintaining intestinal homeostasis by providing innate defense mechanisms for the epithelia. Defensin expression is altered...
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Acute Kidney Injury After Cardiac Surgery in Infants and Children: Evaluation of the Role of Angiotensin-Converting Enzyme Inhibitors
Children with congenital heart disease who undergo cardiac surgery are vulnerable to acute kidney injury (AKI). This study sought to evaluate the role of angiotensin-converting enzyme (ACE) inhibitors and othe...
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Continuous arterial pressure waveform monitoring in pediatric cardiac transplant, cardiomyopathy and pulmonary hypertension patients
A continuous cardiac output monitor based on arterial pressure waveform (FloTrac™/Vigileo™; Edwards Lifesciences, Irvine, CA) is now approved for use in adults but not in children. This device is minimally inv...
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Validation of photographic food records in children: are pictures really worth a thousand words?
Self-reported food records are commonly used to estimate dietary intake. However, diet diaries are time consuming for participants and children are often unfamiliar with standard portion sizes or weights/volum...
