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Article
An experimental study of the mechanism of andrographis paniculata nees (APN) in alleviating the Ca2+-overloading in the process of myocardial ischemie reperfusion
The aim of this experiment is to study the mechanism of APN in alleviating the Ca2+-overloading in dog model during the process of ischemic reperfusion. In comparison with the sustained ischemic group, the parame...
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Article
Effect of captopril on antithrombus function of endothelium
The experimental models of cultured porcine aortic endothelial cells (EC)in vitro were established. 6-keto-prostaglandin F1a (6-keto-PGF1a), thromboxane B2(TXB2)content, plasminogen activator (PA), plasminogen ac...
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Article
Experimental studies on preventive effects of API0134 on vessel reocclusion after thrombolysis
24 model rabbits with femoral arterial thrombosis were divided into two grocps: the treatment group consisting of 12 rabbits which received API0134. and the control group composed of another 12 rabbits. 2 hours a...
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Article
A comparative study of radiofrequency ablation in unipolar and bipolar fashion
In this study we compared the effects of radiofrequency (RF) energy applied to the swine endocardium in a unipolar fashion and in a bipolar one with two different interelectrode distances (5 mm, 10 mm). RF ene...
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Article
Effect of radiofrequency catheter ablation on calcium channel of ventricular myocytes
Using whole-cell patch-clamp technique, the effect of radiofrequency catheter ablation (RFCA) on calcium current (Ica) of guinea pig ventricular myocytes was examined. The radiofrequency energy delivered was 20 W...
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Article
Effects of isoprenaline, phenylephrine on heart and influence of nifedipine on these effects
In a perfused isovolumetrically contracting rat heart model, the effects of isoprenaline (IPN) and phenylephrine (PE) on myocardial contraction and relaxation were investigated, and the influence of nifedipine...
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Article
Effects of amrinone on cardiac contraction and relaxation in isolated, perfused rat heart
The effects of amrinone on cardiac contraction and relaxation were assessed in isolated, perfused rat hearts. It was found that the left ventricular developed pressure (LVDP). dp/dtmax and -da/dtmax did not signi...
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Article
The effect of Andrographis Paniculata Nees (APN) in alleviating the myocardial ischemic reperfusion injury
In experimental dogs, the effect of APN in alleviating the ischemiareperfusion injury was prominent. Compared with the sustained ischemia group, superoxide dismutase (SOD) in the ischemic region of myocardial ...
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Article
Experimental studies on prevention of atherosclerotic arterial stenosis and restenosis after angioplasty with Andrographis Paniculata Nees and Fish Oil
In order to search for effective drugs to reduce restenosis incidence after coronary angioplasty, we studied the effects of a Chinese herb, extract of Andrographis Paniculata Nees (APN), and Fish Oil (FO) on a...
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Article
Effects of captopril on platelet cytosolic free Ca2+ concentrations and on suppression of cell proliferation in culture
In order to investigate the feasibility of angiotensin converting enzyme inhibitors (ACEIs) in preventing the development of atherosclerosis and restenosis after coronary angioplasty and to study their mechani...
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Article
Experiences in intravenous urokinase treatment of 100 AMI patients
From 1980 to 1990 we treated 100 cases of AMI with i.v. urokinase (UK). According to the way of management and the dosage administered all these cases were divided into three groups: first stage of small dosag...
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Article
Protective effects of Andrographis paniculata Nees on post-infarction myocardium in experimental dogs
One hour after the development of myocardial infarction by formation of thrombus, watery extract of Andrographis paniculata Nees (APN) was injected intravenously to 7 dogs for observing the protective effect o...
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Article
Experimental and clinical study of catecholamine—induced hypokalemia in acute myocardial infarction
Adrenaline infusion to 8 rabbits led to remarkable dose-dependent hypokalemia. 2 of them died of ventricular arrhythmia (VA) with severe hypokalemia. In 6 rabbits with i.v. propranolol beforehand, no hypokalem...
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Article
Echocardiographic observation on changes of left ventricular structure and function in healthy elderly
The method of M-mode and 2-dimensional echocardiography was employed in 81 healthy persons to compare the difference in left ventricular structure and function between the elderly group (n = 41, aged 60–76 yea...
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Article
Study on experimental model of coronary artery thrombogenesis and acute myocardial infarction: Changes in epicardial ECG, platelet function and biochemistry, and pathology
A model was produced for formation of coronary artery thrombosis and development of acute myocardial infarction (AMI) in experimental dogs (n= 8) by injuring endothelium of coronary artery with a steel wire, i...
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Article
Significance of changes in plasma atrial natriuretic peptide in congestive heart failure
Plasma atrial natriuretic peptide (pANP) levels were measured in 60 patients with congestive heart failure (CHF) and 69 healthy subjects. Another 29 cardiopathic patients without any sign of CHF also underwent...
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Article
Observation on electrochemical detection method for diagnosis of bacteriuria
The aim of the present work is to detect the presence of bacteriuria by measuring voltage of urine with electrochemical method. 100 specimens of urine were collected from normal persons, to 49 of which bacteri...