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  1. Article

    Open Access

    Loss of Mst1/2 activity promotes non-mitotic hair cell generation in the neonatal organ of Corti

    Mammalian sensory hair cells (HCs) have limited capacity for regeneration, which leads to permanent hearing loss after HC death. Here, we used in vitro RNA-sequencing to show that the Hippo signaling pathway i...

    **aoling Lu, Huiqian Yu, Jiaoyao Ma, Kunkun Wang, Luo Guo in npj Regenerative Medicine (2022)

  2. Article

    Open Access

    FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes

    Upon injury, the liver is capable of substantial regeneration from the original tissue until an appropriate functional size. The underlying mechanisms controlling the liver regeneration processes are not well ...

    Chi-Qian Liang, Deng-Cheng Zhou, Wen-Tao Peng, Wu-Yun Chen in npj Regenerative Medicine (2022)

  3. Article

    Open Access

    Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis

    Cardiovascular disease is the leading cause of death in the world due to losing regenerative capacity in the adult heart. Frogs possess remarkable capacities to regenerate multiple organs, including spinal cor...

    Hai-Yan Wu, Yi-Min Zhou, Zhu-Qin Liao, Jia-Wen Zhong in npj Regenerative Medicine (2021)