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Article
Open AccessFosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis
Cardiovascular disease is the leading cause of death in the world due to losing regenerative capacity in the adult heart. Frogs possess remarkable capacities to regenerate multiple organs, including spinal cor...
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Article
Open AccessFoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes
Upon injury, the liver is capable of substantial regeneration from the original tissue until an appropriate functional size. The underlying mechanisms controlling the liver regeneration processes are not well ...
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Article
Open AccessLoss of Mst1/2 activity promotes non-mitotic hair cell generation in the neonatal organ of Corti
Mammalian sensory hair cells (HCs) have limited capacity for regeneration, which leads to permanent hearing loss after HC death. Here, we used in vitro RNA-sequencing to show that the Hippo signaling pathway i...