15 Result(s)
within
Zengjun **
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessHigh-throughput screening unveils nitazoxanide as a potent PRRSV inhibitor by targeting NMRAL1
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses a major threat to the global swine industry, yet effective prevention and control measures remain elusive. This study unveils Nitazoxanide (NTZ...
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Open AccessRisk of adverse pregnancy outcomes in pregnant women with gestational diabetes mellitus by age: a multicentric cohort study in Hebei, China
Gestational diabetes mellitus (GDM) is an unique metabolic disorder that occurs during pregnancy. Both GDM and advanced age increase the risk of adverse pregnancy outcomes. This study used a GDM cohort study t...
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Open AccessResearch on charge induction law and application of coal samples with different fissures
Indoor testing are performed to explore the charge induction law during the uniaxial compression fracture process of coal samples, and the charge time and frequency domain signals of coal samples with differen...
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Open AccessEfficacy and safety of angiogenesis inhibitors plus immune checkpoint inhibitors in advanced soft tissue sarcoma: a real-world, single-center study
Angiogenesis inhibitors (AIs) and immune checkpoint inhibitors (ICIs) are new treatment options for advanced soft tissue sarcoma (STS) patients. This study evaluated the efficacy and safety of AIs plus ICIs in...
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Open AccessBroadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses
As SARS-CoV-2 Omicron and other variants of concern (VOCs) continue spreading worldwide, development of antibodies and vaccines to confer broad and protective activity is a global priority. Here, we report on ...
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A genomic and epigenomic atlas of prostate cancer in Asian populations
Prostate cancer is the second most common cancer in men worldwide1. Over the past decade, large-scale integrative genomics efforts have enhanced our understanding of this disease by characterizing its genetic and...
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Open AccessThe C.L.A.M.P. Nephrometry score: A system for preoperative assessment of laparoscopic partial nephrectomy with Segmental Renal Artery Clam**
Laparoscopic partial nephrectomy with segmental renal artery clam** is associated with a less warm ischemic injury and better postoperative affected renal function compared with main renal artery clam**. H...
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Open AccessGenome-wide analysis of long noncoding RNA profiling in PRRSV-infected PAM cells by RNA sequencing
Porcine reproductive and respiratory syndrome (PRRS) is a major threat to the global swine industry and causes tremendous economic losses. Its causative agent, porcine reproductive and respiratory syndrome vir...
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Open AccessGenetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population
Insulin-like growth factor 1 (IGF1) and IGF binding protein 3 (IGFBP3) play an important role in the development and progression of renal cell carcinoma (RCC). We evaluated the association of functional polymo...
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Open AccessAbnormal Hypermethylation of the VDAC2 Promoter is a Potential Cause of Idiopathic Asthenospermia in Men
This study aimed to explore the association between the methylation status of the VDAC2 gene promoter region and idiopathic asthenospermia (IAS). Twenty-five IAS patients and 27 fertile normozoospermia (NZ) we...
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Open AccessDevelo** a new score system for patients with PSA ranging from 4 to 20 ng/mL to improve the accuracy of PCa detection
To develop a new score system for patients with prostate specific antigen (PSA) ranging from 4 to 20 ng/mL to improve the accuracy of prostate cancer (PCa) detection, and to evaluate it with receiver operatin...
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Open AccessIntracavernosal metaraminol bitartrate for treatment of priapism resulting from circumcision: a case report
Priapism is an uncommon disorder of involuntary prolonged erection beyond sexual excitement or desire. Herein, we present a rare case of priapism resulting from traditional circumcision under regional anesthes...
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Open AccessRole of genetic mutations in folate-related enzyme genes on Male Infertility
Several studies showed that the genetic mutations in the folate-related enzyme genes might be associated with male infertility; however, the results were still inconsistent. We performed a meta-analysis with t...
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Open AccessEvolution and molecular epidemiology of foot-and-mouth disease virus in China
Foot-and-mouth disease (FMD), caused by foot-and-mouth disease virus (FMDV), is considered one of the most important viral diseases of cloven-hoofed animals, causing severe economic losses in affected regions ...
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Article
Characterization of a PDR type ABC transporter gene from wheat (Triticum aestivum L.)
DON, as a virulence factor, plays an important role in the infection of Fusarium graminearum in wheat. The infection ability of F. graminearum depends on its capacity of producing DON. The production of DON by F....
