-
Article
Improving RSW nugget diameter prediction method: unleashing the power of multi-fidelity neural networks and transfer learning
This research presents an innovative approach to accurately predict the nugget diameter in resistance spot welding (RSW) by leveraging machine learning and transfer learning methods. Initially, low-fidelity (L...
-
Article
Characteristics of tandem repeat inheritance and sympathetic nerve involvement in GAA-FGF14 ataxia
Intronic GAA repeat expansion ([GAA] ≥250) in FGF14 is associated with the late-onset neurodegenerative disorder, spinocerebellar ataxia 27B (SCA27B, GAA-FGF14 ataxia). We aim to determine the prevalence of the G...
-
Article
Open AccessThe Cultural Evolution of Games of Chance
Chance-based gambling has been a recurrent cultural activity throughout history and across many diverse human societies. In this paper, I combine quantitative and qualitative data and present a cultural evolut...
-
Article
Open AccessCirc-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9
CircRNAs are covalently closed, single-stranded RNA that form continuous loops and play a crucial role in the initiation and progression of tumors. Cancer stem cells (CSCs) are indispensable for cancer develop...
-
Article
Open AccessActivation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy
Current immune checkpoint inhibiters (ICIs) have contrasting clinical results in poorly immunogenic cancers such as microsatellite-stable colorectal cancer (MSS-CRC). Therefore, understanding and develo** th...
-
Article
Geriatric nutrition risk index: a more powerful index identifying muscle mass loss in patients with rheumatoid arthritis
To explore the association of geriatric nutrition risk index (GNRI), a traditional albumin-body weight calculation, with myopenia in patients with rheumatoid arthritis (RA) and compare its ability to identify ...
-
Article
STING signaling in islet macrophages impairs insulin secretion in obesity
The innate immune regulator stimulator of interferon genes (STING) mediates self-DNA sensing and leads to the induction of type I interferons and inflammatory cytokines, which promotes the progression of vario...
-
Article
Open AccessAuthor Correction: Increased risk of chronic kidney disease in uric acid stone formers with high neutrophil-to-lymphocyte ratio
-
Article
Open AccessTNFα modulates PANX1 activation to promote ATP release and enhance P2RX7-mediated antitumor immune responses after chemotherapy in colorectal cancer
ATP and its receptor P2RX7 exert a pivotal effect on antitumor immunity during chemotherapy-induced immunogenic cell death (ICD). Here, we demonstrated that TNFα-mediated PANX1 cleavage was essential for ATP r...
-
Article
Open AccessDysfunctional TLR1 reduces the therapeutic efficacy of chemotherapy by attenuating HMGB1-mediated antitumor immunity in locally advanced colorectal cancer
Regional lymph node metastasis is an important predictor for survival outcome and an indicator for postoperative adjuvant chemotherapy in patients with colorectal cancer. Even with advances in adjuvant chemoth...
-
Article
Open AccessIncreased risk of chronic kidney disease in uric acid stone formers with high neutrophil-to-lymphocyte ratio
Urolithiasis is associated with an increased risk of chronic kidney disease (CKD), irrespective of stone compositions. Chronic inflammation is an important factor for CKD progression. Neutrophil-to-lymphocyte ...
-
Article
The Mayo adhesive probability score predicts postoperative fever and intraoperative hemorrhage in mini-percutaneous nephrolithotomy
Contemporary predictive tools for miniaturized percutaneous nephrolithotomy (mPCNL) mainly focus on stone clearance but not perioperative complications, especially infection and hemorrhage. This study aimed to...
-
Article
Nephrolithiasis is associated with the severity of coronary artery calcification, but not with coronary artery stenosis
Emerging data have indicated that nephrolithiasis is possibly associated with subclinical coronary artery disease (CAD). Considering that a significant proportion of obstructive CAD in non-elderly individuals ...
-
Article
Targeting CD73 increases therapeutic response to immunogenic chemotherapy by promoting dendritic cell maturation
The CD39-CD73–adenosinergic pathway converts adenosine triphosphate (ATP) to adenosine for inhibiting anti-tumor immune responses. Therefore, targeting CD73 to reinvigorate anti-tumor immunity is considered th...
-
Article
The Evolution of Inclusive Folk-Biological Labels and the Cultural Maintenance of Meaning
How is word meaning established, and how do individuals acquire it? What ensures the uniform understanding of word meaning in a linguistic community? In this paper I draw from cultural attraction theory and us...
-
Article
The Cultural Evolution of Medical Technologies
When people get ill, they naturally want to restore health through medical interventions. Here I model a situation in which individuals can psychologically entertain multiple potential treatments at once: when...
-
Article
Preparation and characterization of Bi2SiO5/BiVO4 n–n isotype heterojunction composites as a visible-light-induced photocatalyst for tetracycline and levofloxacin degradation
Semiconductor photocatalysis is a promising method to solve the problem of antibiotic pollution in water. A series of Bi2SiO5/BiVO4 composite photocatalysts for tetracycline and levofloxacin degradation are prepa...
-
Article
Open AccessPrevalence of polycystic ovary syndrome under NIH criteria among the tenth-grade Chinese schoolgirls in Guangzhou area: a cross-sectional epidemiological survey
Polycystic ovary syndrome (PCOS) is currently considered to have a peri-adolescence onset and continuously influence the reproductive and metabolic health of the patients, while the diagnostic criteria among a...
-
Chapter and Conference Paper
Composite Evaluation of Coalbed Methane Fields Based on Structure and Stress Characteristics-Case Study of B Field in Bowen Basin
The Permian Triassic Bowen basin is located in New South Wales and Queensland along the eastern coast of Australia. The basin is a back arc foreland basin. The complexity of structural evolution leads to the c...
-
Article
Synthesis, characterization and photocatalytic properties of In2.77S4/Ti3C2 composites
Recently, the problem of water pollution, caused by antibiotics, is becoming more and more serious. Photocatalysis is one of the promising technologies for removing antibiotics from water. Herein, the In2.77S4/Ti
