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  1. Article

    Open Access

    Radiated glioblastoma cell-derived exosomal circ_0012381 induce M2 polarization of microglia to promote the growth of glioblastoma by CCL2/CCR2 axis

    Radiotherapy is the primary therapeutic option for glioblastoma. Some studies proved that radiotherapy increased the release of exosomes from cells. The mechanism by which these exosomes modify the phenotype o...

    Chunzhi Zhang, Yuan Zhou, Ya Gao, Ze Zhu in Journal of Translational Medicine (2022)

  2. Article

    Open Access

    The genetic basis for inactivation of Wnt pathway in human osteosarcoma

    Osteosarcoma is a highly genetically unstable tumor with poor prognosis. We performed microarray-based comparative genomic hybridization (aCGH), transcriptome sequencing (RNA-seq), and pathway analysis to gain...

    **aoling Du, Jilong Yang, Da Yang, Wei Tian, Ze Zhu in BMC Cancer (2014)