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  1. No Access

    Chapter

    Role of Regulatory T Lymphocytes in Health and Disease

    T cells are conventionally categorized into two basic types, viz., CD4+ helper and CD8+ cytotoxic T cells. CD4+ T cells were known to “help” in the activation and differentiation of various immune cells such as N...

    Niti Shokeen, Chaman Saini, Leena Sapra, Zaffar Azam in Systems and Synthetic Immunology (2020)

  2. No Access

    Chapter

    A Chronological Journey of Breg Subsets: Implications in Health and Disease

    B cells play a multidimensional role in host immunity. Regulatory B (Breg) cells are a class of B lymphocytes with immunomodulatory properties that play an important role in maintaining immunological tolerance...

    Hamid Y. Dar, Lekha Rani, Leena Sapra, Zaffar Azam in Systems and Synthetic Immunology (2020)

  3. No Access

    Chapter

    Neuronal Nitric Oxide Synthase (nNOS) in Neutrophils: An Insight

    NO (nitric oxide) is an important regulator of neutrophil functions and has a key role in diverse pathophysiological conditions. NO production by nitric oxide synthases (NOS) is under tight control at transcri...

    Rashmi Saini, Zaffar Azam, Leena Sapra in Reviews of Physiology, Biochemistry and Ph… (2021)

  4. Article

    Open Access

    Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice

    Osteoporosis is a systemic-skeletal disorder characterized by enhanced fragility of bones leading to increased rates of fractures and morbidity in large number of populations. Probiotics are known to be involv...

    Leena Sapra, Hamid Y. Dar, Asha Bhardwaj, Amit Pandey, Surbhi Kumari in Scientific Reports (2021)

  5. No Access

    Article

    “Immunoporosis”: Immunology of Osteoporosis

    Bone is a dynamic organ that maintains its proper architecture and function by undergoing continuous cycles of modelling and remodelling during normal host physiology. Any dysregulation in the bone remodelling...

    Leena Sapra, Zaffar Azam, Lekha Rani in Proceedings of the National Academy of Sci… (2021)

  6. No Access

    Chapter

    Applications of Cellulose in Biobased Food Packaging Systems

    Packaging has a major impact on ensuring the purity and safety of food, reducing waste and spoilage. Biopolymer-based packaging is a modern alternative to traditional plastic packing systems that is gaining po...

    Priyanka Gupta, Neelam, Kalpana Baghel, Versha Sharma in Biobased Packaging Materials (2023)

  7. Article

    Open Access

    Withaferin-A attenuates diabetes mellitus induced male reproductive dysfunction mediated by ERα in brain and testes of Swiss albino mice

    Diabetes mellitus (DM) is a chronic metabolic disease, characterized by persistent hyperglycemia resulting from diminished insulin secretion or insulin resistance. The present study evaluated the ameliorative ...

    Kalpana Baghel, Zaffar Azam, Rashmi Srivastava, Neelima Gupta in Scientific Reports (2023)

  8. No Access

    Chapter

    Biobased Nanomaterials in Regenerative Medicines

    Due to its astounding ability to restore injured tissues using biobased nanomaterials, regenerative medicine has engrossed higher consideration in recent years. The physicochemical properties of nanoparticles ...

    Mukesh Kumar Niranjan, Kalpana Baghel, Zaffar Azam in Biobased Nanomaterials (2024)