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  1. Article

    c-Abl–p38α signaling plays an important role in MPTP-induced neuronal death

    Oxidative stress is a major cause of sporadic Parkinson’s disease (PD). Here, we demonstrated that c-Abl plays an important role in oxidative stress-induced neuronal cell death. C-Abl, a nonreceptor tyrosine k...

    R Wu, H Chen, J Ma, Q He, Q Huang, Q Liu, M Li, Z Yuan in Cell Death & Differentiation (2016)

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  2. Article

    Open Access

    Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner

    Chemoresistance in cancer has previously been attributed to gene mutations or deficiencies. Bax or p53 deficiency can lead to resistance to cancer drugs. We aimed to find an agent to overcome chemoresistance i...

    W Guo, Y Zhang, Z Ling, X Liu, X Zhao, Z Yuan, C Nie, Y Wei in Cell Death & Disease (2015)

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  3. Article

    Open Access

    Caspase-9 mediates Puma activation in UCN-01-induced apoptosis

    The protein kinase inhibitor 7-hydroxystaurosporine (UCN-01) is one of the most potent and frequently used proapoptotic stimuli. The BH3-only molecule of Bcl-2 family proteins has been reported to contribute t...

    C Nie, Y Luo, X Zhao, N Luo, A Tong, X Liu, Z Yuan, C Wang, Y Wei in Cell Death & Disease (2014)

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  4. Article

    Open Access

    αNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells

    Nascent polypeptide-associated complex α (αNAC) is reportedly overexpressed in several types of cancers and regulates cell apoptosis under hypoxic conditions in HeLa cells. The aim of our study was to investigate...

    W Zeng, J Zhang, M Qi, C Peng, J Su, X Chen, Z Yuan in Cell Death & Disease (2014)

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  5. No Access

    Chapter and Conference Paper

    Functional Analysis of Genes of Unknown Functions in Sinorhizobium meliloti 1021

    J. Cheng, J. Fowler, A. Cowie, R. Zaheer… in Biological Nitrogen Fixation, Sustainable … (2005)