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  1. Article

    Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity

    Beta cell inflammation and cytokine-induced toxicity are central to autoimmune diabetes development. Lipid mediators generated upon lipoxygenase (LO) activation can participate in inflammatory pathways. 12LO-d...

    M. Chen, Z. D. Yang, K. M. Smith, J. D. Carter, J. L. Nadler in Diabetologia (2005)

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  2. Article

    The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice

    Aims/hypothesis. Pro-inflammatory cytokines are increased during the active stages of Type I (insulin-dependent) diabetes mellitus. The aim of this study was to investigate the applicability of u...

    Z.-D. Yang, M. Chen, R. Wu, M. McDuffie, J.-L. Nadler in Diabetologia (2002)

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