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Article
Regioselective acylation of 2′- or 3′-hydroxyl group in salicin: Hemisynthesis of acylated salicins
Salicin-based phenolic glycosides(PGs) are important defensive substances against herbivore feeding and have good bioactivities. In this work, a novel approach for the synthesis of salicin-based PGs has been d...
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Article
Open AccessReal-time and label-free analysis of binding thermodynamics of carbohydrate-protein interactions on unfixed cancer cell surfaces using a QCM biosensor
A novel approach to the study of binding thermodynamics and kinetics of carbohydrate-protein interactions on unfixed cancer cell surfaces using a quartz crystal microbalance (QCM) biosensor was developed, in w...
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Article
A Novel Self-Diverting Fracturing Technology Based on Inverse Phase Transformation
A self-diverting fracturing technology is proposed in the study as a way of effectively creating a stimulated reservoir volume. The technology, which is based on the use of a novel self-diverting fracturing fl...
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Article
Thermo-responsive temporary plugging agent based on multiphase transitional supramolecular gel
In this study, a thermo-responsive temporary plugging agent was developed with the property of sol-gel-sol transition behavior at different temperatures. At low temperature, the material is in sol state, while in...
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Article
Open AccessComprehensive approach to weaning in difficult-to-wean infantile and juvenile-onset glycogen-storage disease type II patients: a case series
Glycogen storage disease type II (GSD II) is caused by acid alpha-glucosidase (GAA) deficiency. Both infantile-onset and juvenile-onset GSD II lead to proximal muscle weakness and respiratory insufficiency and...
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Article
Open AccessAnti-aphrodisiac pheromone, a renewable signal in adult butterflies
The male butterfly Pieris napi produces the anti-aphrodisiac pheromone methyl salicylate (MeS) and transfers it to the female during mating. After mating she releases MeS, when courted by conspecific males, which...
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Article
Open AccessMelatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop
The inflammatory response is induced by the overexpression of inflammatory cytokines, mainly interleukin (IL)-1β, and is one of the main causes of intervertebral disc degeneration (IVDD). NLR pyrin domain cont...
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Article
Open AccessSimulation of multiphase flow pattern, effective distance and filling ratio in hydraulic fracture
Hydraulic fracturing is a key measure to increase production and transform oil and gas reservoirs, which plays an important role in oil and gas field development. Common hydraulic fracturing is of inevitable b...
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Article
Open AccessEvaluation of the safety and efficacy of low-dose rasburicase in critically ill children with haematological malignancies
Background The recommended dose of rasburicase is quite expensive, thus limiting its use. Whether a lower dose of rasburicase would be equally effective for critically ill children, who often have more complicate...
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Chapter and Conference Paper
Successful Application of Self-prop** Fracturing Fluid System in Volume Fracturing of Tight Reservoir
The volume fracturing technology characterized by large-scale, large displacement, segmented multi cluster perforation and high slick water ratio has effectively developed tight reservoirs. However, tight oil ...
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Article
Open AccessMisdiagnosed Branchio-Oto-Renal syndrome presenting as proteinuria and renal insufficiency with insidious signs since early childhood: a report of three cases
Branchio-oto-renal (BOR) syndrome is an inherited multi-systemic disorder. Auricular and branchial signs are highly suggestive of BOR syndrome but often develop insidiously, leading to a remarkable misdiagnosi...
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Chapter and Conference Paper
Physical Performance Test of Self-prop** Solid and Evaluation of the Propped-Fracture Conductivity
In order to solve problems such as sand blockage, equipment wear, and residue damage associated with the current fracturing technology, we develop a method to form self-prop** solid (SPS) proppant under form...
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Article
Supramolecular systems for bioapplications: recent research progress in China
Supramolecular systems feature dynamic, reversible and stimuli-responsive characteristics, which are not easily achieved by molecular entities. The last decade has witnessed tremendous advances in the investig...