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Article
Open AccessPrognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China
The outcomes of children with acute lymphoblastic leukemia (ALL) have been incrementally improved with risk-directed chemotherapy but therapy responses remain heterogeneous. Parameters with added prognostic va...
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Article
Data-driven evaluation and optimization of the sustainable development of the logistics industry: case study of the Yangtze River Delta in China
In this study, a data-driven way is proposed to evaluate and optimize the sustainable development of the logistics industry (LI). Based on a comprehensive consideration of economic, societal, and environmental...
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Article
Open AccessPoor treatment responses were related to poor outcomes in pediatric B cell acute lymphoblastic leukemia with KMT2A rearrangements
The KMT2A gene, formerly named the MLL gene, is rearranged (KMT2Ar) in 70–75% of infants, 5–6% of children and 10–15% of adult patients with B cell acute lymphoblastic leukemia (B-ALL). The outcome after chemothe...
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Article
Open AccessMorphological variation in Cynodon dactylon (L.) Pers., and its relationship with the environment along a longitudinal gradient
Geographical variation in morphological traits may reflect evolutionary patterns of morphological adaptability along environmental gradients. Comprehensive information on longitudinal patterns of morphological...
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Article
Open AccessVariation in ploidy level and genome size of Cynodon dactylon (L.) Pers. along a latitudinal gradient
Knowledge of ploidy level and genome size in a germplasm collection is critical before studying genetic diversification of different environmental range in grasses and other plants. We assessed the geographic ...
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Article
Open AccessVariations in morphological traits of bermudagrass and relationship with soil and climate along latitudinal gradients
This complex environmental heterogeneity coupled with the long-standing history offers scenario suitable for and favoring the evolution and existence of variation of morphological traits.
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Article
Open AccessFunctional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1
The novel gene HA117 is a multidrug resistance (MDR) gene expressed by all-trans retinoic acid-resistant HL-60 cells. In the present study, we compared the multidrug resistance of the HA117 with that of the cl...
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Article
Open AccessHA117 gene increased the multidrug resistance of K562 cells in vitro: an investigation to the function of a novel gene related to drug resistance
A novel multi-drug resistance gene named as HA117 has been screened and cloned in multidrug resisitant leukemia cell lines in our previous research, but its function is still unknown. In this study, HA117 gene...
