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  1. Article

    Open Access

    When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers?

    Whether and when glomerular filtration rate (GFR) in preterms catches up with term peers is unknown. This study aims to develop a GFR maturation model for (pre)term-born individuals from birth to 18 years of a...

    Yunjiao Wu, Karel Allegaert, Robert B. Flint in Pharmaceutical Research (2024)

  2. Article

    Open Access

    Maturation of Paracetamol Elimination Routes in Preterm Neonates Born Below 32 Weeks of Gestation

    Despite being off-label, intravenous paracetamol (PCM) is increasingly used to control mild-to-moderate pain in preterm neonates. Here we aim to quantify the maturation of paracetamol elimination pathways in p...

    Yunjiao Wu, Swantje Völler, Elke H. J. Krekels in Pharmaceutical Research (2023)

  3. Article

    Open Access

    Prediction of glomerular filtration rate maturation across preterm and term neonates and young infants using inulin as marker

    Describing glomerular filtration rate (GFR) maturation across the heterogeneous population of preterm and term neonates and infants is important to predict the clearance of renally cleared drugs. This study ai...

    Yunjiao Wu, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons in The AAPS Journal (2022)