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    Article

    Single-cell RNA sequencing reveals cellular and molecular immune profile in a Pembrolizumab-responsive PD-L1-negative lung cancer patient

    High expression of PD-L1 predicts PD-1/PD-L1 inhibitor benefit, meanwhile a few PD-L1-negative patients still benefit from these drugs. In this study, we aimed to explore the underlying cellular and molecular ...

    Runbo Zhong, Yunbin Zhang, Dongfang Chen, Shuhui Cao… in Cancer Immunology, Immunotherapy (2021)