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Article
Expression of structural proteins of hepatitis C virus (HCV) in mammalian cells
The vaccinia viral vector containing T7 promoter was used to construct the expression plasmids carrying HCV structural genes of C, El and E2/NS1. These genes were transiently expressed in mammalian cells in th...
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Article
A magnetoelectric-based broadband vibration energy harvester for powering wireless sensors
Scavenging vibration energy directly from environments is an attractive technique for potentially powering small and/or wireless electronic devices in a smart structure and system. In this paper, a novel broad...
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Article
Investigation of magnetostrictive/piezoelectric multilayer composite with a giant zero-biased magnetoelectric effect
In this paper, we investigate the resonance magnetoelectric (ME) effect in the middle supported multilayer composites consisting of high-permeability Fe-based nanocrystalline soft magnetic alloy Fe73.5Cu1Nb3Si13....
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Article
Interaction of viruses with host immune system and immunomodulation in chronic viral infections
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Article
Vaccine therapies for chronic hepatitis B: can we go further?
Chronic hepatitis B is a major health burden worldwide. In addition to the recent progress in antiviral treatment, therapeutic vaccination is a promising new strategy for the control of chronic hepatitis B. On...
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Article
Energy Harvesting from Ambient Vibrations with Arbitrary In-Plane Motion Directions Using a Magnetostrictive/Piezoelectric Laminate Composite Transducer
A magnetoelectric (ME) vibration energy harvester has been designed to scavenge sufficient energy from ambient vibration with arbitrary motion directions in a plane and over a range of frequencies. In the harv...
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Article
Open AccessSuppression of established hepatocarcinoma in adjuvant only immunotherapy: alum triggers anti-tumor CD8+ T cell response
Dendritic cell-based immunotherapy is a new weapon in our battle against malignancies in human. Recent trials in human and research work in model animals have shown various degrees of success, suggesting its g...
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Article
Enhanced Broadband Vibration Energy Harvesting Using a Multimodal Nonlinear Magnetoelectric Converter
In this work, we present a multimodal wideband vibration energy harvester designed to scavenge energy from ambient vibrations over a wide frequency range. The harvester consists of a folded cantilever, three m...
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Article
Long-term green manure application improves soil K availability in red paddy soil of subtropical China
Potassium (K) in soil minerals is an important factor affecting rice production in red paddy soil of subtropical China under intensive agricultural production. The long-term application of green manure might a...
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Article
Open AccessPregnancy-related acute kidney injury at high altitude: a retrospective observational study in a single center
Pregnancy-related acute kidney injury (Pr-AKI) is associated with maternal and fetal morbidity and mortality. There are few studies focusing on Pr-AKI at high altitude in the literature.
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Open AccessNovel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern, including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Omicron (B.1.1.529) has aroused...
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A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding
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Open AccessAn ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope
New threats posed by the emerging circulating variants of SARS-CoV-2 highlight the need to find conserved neutralizing epitopes for therapeutic antibodies and efficient vaccine design. Here, we identified a re...
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Open AccessCombating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
The highly mutated and transmissible Omicron (BA.1) and its more contagious lineage BA.2 have provoked serious concerns over their decreased sensitivity to the current COVID-19 vaccines and evasion from most a...
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Article
A broadly neutralizing antibody inhibits SARS-CoV-2 variants through a novel mechanism of disrupting spike trimer integrity
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Article
Self-powered piezoelectric energy harvesting with ultra-low power consumption for low-amplitude ambient vibrations
The consumption of high power and an extended start-up time are some of the major issues faced by piezoelectric energy harvesting. With this in mind, a control circuit with an extremely low power consumption o...
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Article
Open AccessA bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses
The Omicron subvariants BQ.1.1, XBB.1.5, and XBB.1.16 of SARS-CoV-2 are known for their adeptness at evading immune responses. Here, we isolate a neutralizing antibody, 7F3, with the capacity to neutralize all...
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Article
Experimental investigation on bond performance of UHPFRC wet joint by direct tension test
Ultra-high-performance fiber-reinforced concrete (UHPFRC) is applied to joint nodes with its excellent mechanical properties, which helps to improve the force transfer performance of UHPFRC structures. The str...
