31 Result(s)
within
Yukio Yamada
English
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Article
Ultrastructural demonstration of calcitonin in osmium-fixed human medullary carcinoma of thyroid by the protein A-colloidal gold technique
In two medullary carcinomas of the thyroid gland two types of secretory granules were found electron microscopically in the cytoplasm of the tumour cells. The sizes of the granules in one case ranged 103–345 n...
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Article
Absorption Coefficient Measurements of Strongly Scattering Media Using Time-Resolved Transmittance of a Short Pulse in Near-Infrared (NIR) Wavelength Range
Absorption coefficient measurements of strongly scattering and weakly absorbing media have been performed using time resolved transmittance of a 100 fs pulse through a 30 mm slab containing latex spheres suspe...
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Article
Assessment of mitotic activity in pituitary adenomas and carcinomas
Assessment of mitotic activity represents one of the oldest and most routinely used histopathologic methods of evaluating the biological aggressiveness of human tumors. In the case of pituitary tumors, however...
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Article
Frequency-Domain Measurements of Diffusing Photon Propagation in Solid Phantoms
Photon propagation in a highly scattering medium such as living tissue is well described by the photon diffusion equation. In a homogeneous and isotropic case, the equation has analytically been solved for a m...
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Article
Determination of the Asymmetry Parameter and Scattering Coefficient of Turbid Media from Spatially Resolved Reflectance Measurements
We present a technique for determining the asymmetry parameter and scattering coefficient of turbid media from spatially resolved reflectance measurements. This technique will contribute to the development of ...
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Article
Explanation of Human Skin Color by Multiple Linear Regression Analysis Based on the Modified Lambert-Beer Law
Quantitative analysis of human skin color is needed in the medical and cosmetic fields. Because of the strong light scattering by biological tissues, however, analysis of skin color has not yet been fully succ...
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Article
Time-Resolved Measurements of in vivo Optical Properties of Piglet Brain
The in vivo optical properties of a piglet brain were measured using a time-resolved system at three different wavelengths (759, 794, 824 nm). To separate the contribution of different head layers to the detected...
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Article
Fundamental Studies of Photon Migration in Biological Tissues and Their Application to Optical Tomography
This paper reviews the studies of photon migration in biological tissues and its application to optical tomography which were conducted in the Mechanical Engineering Laboratory of Japan’s Ministry of Internati...
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Chapter
Development of a Retractor for Monitoring the Oxygenation State of Brain Tissue
In the majority of neurosurgical operations, brain refraction is one of the essential techniques. When the stress of retraction becomes too high, because of the occlusion of the blood vessel, saturation of oxy...
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Article
Temperature-Insensitive Measurement of Glucose Concentration Based on Near Infrared Spectroscopy and Partial Least Squares Analysis
Temperature-insensitive partial least squares analysis for glucose measurement is presented based on Near Infrared spectroscopy in the wavelength range from 1,250 to 1,800nm. Experiments are performed using aq...
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Article
Instrumental Requirements for Non-Invasive Blood Glucose Measurement Using NIR Spectroscopy
The magnitude of spectral change in blood glucose measurements with diffuse reflectance spectroscopy is investigated. Spectral change is estimated by simulation of light propagation in skin tissue and measurem...
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Article
Fundamental Study of Reflection Pulse Oximetry
For the purpose of develo** reflection pulse oximetry, we have analyzed the light propagation in tissue to calculate the photon-visit depth for reflected light and to estimate the measured intensities of tra...
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Article
Microbial synthesis of (R)- and (S)-3,4-dimethoxyamphetamines through stereoselective transamination
Two soil isolates, Arthrobacter sp. KNK168 and Pseudomonas sp. KNK425, aminated 3,4-dimethoxyphenylacetone in presence of sec-butylamine as an amino donor to yield 3,4-dimethoxyamphetamine (DMA) with different en...
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Article
Monte Carlo Simulation of Near Infrared Reflectance Spectroscopy in the Wavelength Range from 1000 nm to 1900 nm
We have calculated the characteristics of reflected near infrared light, which is incident on the skin surface, scattered in the skin tissue and detected, in the wavelength range from 1000 nm to 1900 nm. We ha...
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Article
Surgical Treatment for an Atherosclerotic Aneurysm of the Superficial Femoral Artery: Report of a Case
We report the case of an isolated atherosclerotic aneurysm of the superficial femoral artery (SFA). The patient was a 76-year-old man who presented with intermittent claudication and muscle weakness in his rig...
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Article
The Development of Leukocyte Counter Using Fluorescence Imaging Analysis
Image cytometry centrifugation (ICC) method has been developed and applied to count residual leukocytes in transfusion blood products for quality assurance testing. The standard leukocyte fluorescence image pr...
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Article
Influences of Target Size and Contrast on Near Infrared Diffuse Optical Tomography – a Comparison Between Featured-data and Full Time-resolved Schemes
Our recent diffuse optical tomography experiments on human lower legs and forearms are presented using the time-resolved measuring system and image reconstruction algorithm based on the modified generalized pu...
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Article
Light propagation for time-domain fluorescence diffuse optical tomography by convolution using lifetime function
Time-domain light propagation in biological tissue is studied by solving the forward problem for fluorescence diffuse optical tomography using a convolution of the zero-lifetime emission light and the exponent...
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Article
Effects of spatial variation of skull and cerebrospinal fluid layers on optical map** of brain activities
In order to investigate the effects of anatomical variation in human heads on the optical map** of brain activity, we perform simulations of optical map** by solving the photon diffusion equation for layer...
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Chapter and Conference Paper
3D Analysis of Intracortical Microvasculature During Chronic Hypoxia in Mouse Brains
The purpose of this study is to determine when and where the brain microvasculature changes its network in response to chronic hypoxia. To identify the hypoxia-induced structural adaptation, we longitudinally ...
