2,359 Result(s)
within
Yuan-yuan **e
-
Article
Open AccessThe effects of anastomoses between anterior and posterior circulation on postoperative prognosis of patients with moyamoya disease
Moyamoya disease (MMD) is a chronic ischemic cerebrovascular disease. Collateral circulation in MMD has emerged as a research focus. Our aims were to assess the impact of anastomoses between the anterior and p...
-
Article
Utilizing procalcitonin, C-reactive protein, and serum amyloid A in combination for diagnosing sepsis due to urinary tract infection
In this study, we aimed to evaluate the combined diagnostic value of procalcitonin (PCT), C-reactive protein (CRP), and serum amyloid A (SAA) in sepsis caused by urinary tract infection.
-
Article
Is postmastectomy radiotherapy necessary for breast cancer patients with clinically node-positive downstaging to ypN0 after neoadjuvant chemotherapy?
The significance of postmastectomy radiotherapy (PMRT) in breast cancer patients who initially have clinically node-positive (cN +) status but achieve downstaging to ypN0 following neoadjuvant chemotherapy (NA...
-
Article
UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals Potential Anti-tumor Mechanism of Banxia **exin Decoction in Colorectal Cancer Mice
To clarify the potential mechanism of Banxia **exin Decoction (BXD) on colorectal cancer (CRC) from the perspective of metabolomics.
-
Article
Open AccessChromosome-level genome assembly of a cliff plant Taihangia rupestris var. ciliata provides insights into its adaptation and demographic history
Cliffs are recognized as one of the most challenging environments for plants, characterized by harsh conditions such as drought, infertile soil, and steep terrain. However, they surprisingly host ancient and d...
-
Article
Open AccessLINC00525 enhances ZNF460-regulated CD24 expression through the sponge miR-125a-5p to promote malignant progression of breast cancer
CD24 is a highly glycosylated glycosylphosphatidylinositol anchored membrane protein that plays an important role in tumor progression. The aim of this study was to investigate the effect of abnormal expressio...
-
Article
Open AccessA software for calculating coal mine gas emission quantity based on the different-source forecast method
The ability to predict gas emissions accurately is pivotal in managing gas control and ensuring safe mining operations. Existing internationally acknowledged gas control and prediction software does not cater ...
-
Article
Open AccessPreliminary research on LncRNA ATP2B2-IT2 in neovascularization of diabetic retinopathy
Diabetic retinopathy (DR) is a common complication of diabetes, and recent findings have shown that long noncoding RNAs (lncRNAs) may be involved in its pathogenesis. Through bioinformatics analysis, we found ...
-
Article
Open AccessWeChat assisted electronic symptom measurement for patients with adenomyosis
Symptom assessment is central to appropriate adenomyosis management. Using a WeChat mini-program-based portal, we aimed to establish a valid symptom assessment scale of adenomyosis (AM-SAS) to precisely and ti...
-
Article
Cinnamaldehyde Regulates the Migration and Apoptosis of Gastric Cancer Cells by Inhibiting the Jak2/Stat3 Pathway
Gastric cancer is a malignant tumor with high morbidity and mortality all around the world. Because of its poor prognosis and low survival rate, the treatment of gastric cancer has received extensive attention...
-
Article
Open AccessGut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions
Gut microbiota (GM) have been implicated as important regulators of gastrointestinal symptom which is commonly occurred along with respiratory influenza A virus (IAV) infection, suggesting the involvement of t...
-
Article
Open AccessNeoadjuvant talazoparib in patients with germline BRCA1/2 mutation-positive, early-stage triple-negative breast cancer: exploration of tumor BRCA mutational status
Talazoparib monotherapy in patients with germline BRCA-mutated, early-stage triple-negative breast cancer (TNBC) showed activity in the neoadjuvant setting in the phase II NEOTALA study (NCT03499353). These bioma...
-
Article
Height-dependent differential rotation of the solar atmosphere detected by CHASE
Rotation is an intrinsic property of stars and provides essential constraints on their structure, formation, evolution and interaction with the interplanetary environment. The Sun provides a unique opportunity...
-
Article
Novel pleiotropic variants associated with type 2 diabetes and polycystic ovary syndrome detected using a pleiotropic cFDR method
Genome-wide association studies (GWASs) on polycystic ovary syndrome (PCOS) and type 2 diabetes (T2D) are usually conducted as single trait, rather than a simultaneous analysis of the related traits. Therefore...
-
Article
Open AccessDownregulation of enhancer RNA AC003092.1 is associated with poor prognosis in kidney renal clear cell carcinoma
Kidney renal clear cell carcinoma (KIRC) is the most common histological type of renal cancer, enhancer RNA plays a significant role in tumor growth, however, it has been less studied in renal cancer. The aim ...
-
Article
Open AccessMacrophage and fibroblast trajectory inference and crosstalk analysis during myocardial infarction using integrated single-cell transcriptomic datasets
Cardiac fibrosis after myocardial infarction (MI) has been considered an important part of cardiac pathological remodeling. Immune cells, especially macrophages, are thought to be involved in the process of fi...
-
Article
Open AccessSingle molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation
LRRK2-targeting therapeutics that inhibit LRRK2 kinase activity have advanced to clinical trials in idiopathic Parkinson’s disease (iPD). LRRK2 phosphorylates Rab10 on endolysosomes in phagocytic cells to prom...
-
Article
Structure and dynamics of microbial communities associated with the resurrection plant Boea hygrometrica in response to drought stress
The resurrection plant Boea hygrometrica selectively recruits and assembles drought-specific microbial communities across the plant–soil compartments, which may benefit plant growth and fitness under extreme drou...
-
Article
Open AccessDevelopment of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase
DNA base editors enable direct editing of adenine (A), cytosine (C), or guanine (G), but there is no base editor for direct thymine (T) editing currently. Here we develop two deaminase-free glycosylase-based b...
-
Article
New asymmetric quantum codes from matrix-product codes
In this paper, we provide the method of constructing asymmetric quantum codes by means of the Euclidean sums of matrix-product codes over finite fields. We construct asymmetric quantum codes of length 2n by using...
