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Efficacy and safety of entecavir compared to lamivudine in nucleoside-naïve patients with chronic hepatitis B: a randomized double-blind trial in China

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  1. Article

    Efficacy and safety of entecavir compared to lamivudine in nucleoside-naïve patients with chronic hepatitis B: a randomized double-blind trial in China

    Guangbi Yao, Chengwei Chen, Weilun Lu, Hong Ren, Deming Tan in Hepatology International (2008)

  2. Article

    Open Access

    Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naïve Chinese patients with chronic hepatitis B: a randomized, multicenter study

    Entecavir demonstrated superior virologic and biochemical benefits over lamivudine at 48 weeks in nucleoside-naïve Chinese patients with chronic hepatitis B (CHB). We evaluated the effect of continued entecavi...

    Guangbi Yao, ChengWei Chen, WeiLun Lu, Hong Ren, DeMing Tan in Hepatology International (2008)

  3. Article

    Open Access

    Long-term outcomes after nucleos(t)ide analogues discontinuation in chronic hepatitis B patients with HBeAg-negative

    Hepatitis B e Antigen (HBeAg)-negative chronic hepatitis B (CHB) patients have an active liver disease with a high risk of progression to decompensated cirrhosis and hepatocellular carcinoma. The management st...

    Dengming He, Shimin Guo, Wen Chen, **anli Chen, Guohua Yan in BMC Infectious Diseases (2013)

  4. Article

    Open Access

    Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B

    The long-term goal of chronic hepatitis B (CHB) treatment is improvement of liver disease and prevention of cirrhosis. The aim of this study was to assess whether prolonged telbivudine treatment improves liver...

    **-Lin Hou, Daozheng Xu, Guangfeng Shi, Mobin Wan, Zachary Goodman in Advances in Therapy (2015)

  5. Article

    Open Access

    Sustained serological and complete responses in HBeAg-positive patients treated with Peginterferon alfa-2b: a 6-year long-term follow-up of a multicenter, randomized, controlled trial in China

    Pegylated interferon (PEG-IFN) alfa-2b is recommended for chronic hepatitis B (CHB). We aimed to investigate the sustainability of off-treatment responses among Chinese HBeAg-positive CHB patients treated with...

    Jian Sun, Huiguo Ding, Guofeng Chen, Guiqiang Wang, Lai Wei in BMC Gastroenterology (2019)

  6. Article

    Open Access

    Risk factors and risk prediction models for colorectal cancer metastasis and recurrence: an umbrella review of systematic reviews and meta-analyses of observational studies

    There is a clear need for systematic appraisal of models/factors predicting colorectal cancer (CRC) metastasis and recurrence because clinical decisions about adjuvant treatment are taken on the basis of such ...

    Wei Xu, Yazhou He, Yuming Wang, Xue Li, Jane Young, John P. A. Ioannidis in BMC Medicine (2020)

  7. Article

    Open Access

    ECMO-assisted resection of left main bronchial malignant tumor and left pneumonectomy with comprehensive nursing support: a case report

    Patients with Extracorporeal Membrane Oxygenation (ECMO) undergoing primary bronchial malignancy resection and left pneumonectomy via bilateral thoracic approach are rare for there exist few reports available ...

    Hui Yang, Ruiyun Chen, **gru Chen, Fan Yan in Journal of Cardiothoracic Surgery (2020)

  8. Article

    Open Access

    PD-L1 expression in ovarian clear cell carcinoma using the 22C3 pharmDx assay

    Ovarian clear cell carcinoma (OCCC), well known for its chemoresistance to platinum-based chemotherapy, exhibited a good response in clinical trials of anti–PD-1/PD-L1 inhibitors. By assessing PD-L1 expression...

    Yike Gao, Boju Pan, Hongbao Jia, Yang Zhang, Shu Wang, Yuming Wang in Diagnostic Pathology (2024)