-
Article
Verification of the resistance of a LEA gene from Tamarix expression in Saccharomyces cerevisiae to abiotic stresses
The role of late embryogenesis abundant (LEA) proteins in stress tolerance was examined by using a yeast expression system. LEA protein tolerance to the abotic stresses in plants involved in salt, drought and ...
-
Article
Open AccessThe C-terminal sequence of the large hepatitis delta antigen is variable but retains the ability to bind clathrin
Hepatitis delta virus (HDV) is a defected RNA virus and requires its encoded large antigen (LDAg) to interact with helper viral proteins (HBsAgs) during assembly. Recently, a study demonstrated a direct bindin...
-
Article
A ThCAP gene from Tamarix hispida confers cold tolerance in transgenic Populus (P. davidiana × P. bolleana)
The ThCAP gene, which encodes a cold acclimation protein, was isolated from a Tamarix hispida NaCl-stress root cDNA library; its expression patterns were then assayed by qRT-PCR in different T. hispida tissues tr...
-
Article
Enhanced salt tolerance of transgenic poplar plants expressing a manganese superoxide dismutase from Tamarix androssowii
Superoxide dismutases (SODs) play important role in stress tolerance of plants. In this study, an MnSOD gene (TaMnSOD) from Tamarix androssowii, under the control of the CaMV35S promoter, was introduced into popl...
-
Article
ThPOD3, a truncated polypeptide from Tamarix hispida, conferred drought tolerance in Escherichia coli
The ThPOD1 gene encodes a peroxidase and was isolated from a Tamarix hispida NaCl-stress root cDNA library. We found that ThPOD1 expression could be induced by abiotic stresses such as cold, salt, drought and exo...
-
Article
Cloning and characterization of a chitinase gene Lbchi31 from Limonium bicolor and identification of its biological activity
Chitinases are digestive enzymes that break down glycosidic bonds in chitin. In the current study, an endochitinase gene Lbchi31 was cloned from Limonium bicolor. The cDNA sequence of Lbchi31 was 1,107 bp in leng...
-
Article
Cloning, Heterologous Expression, and Functional Characterization of a Chitinase Gene, Lbchi32, from Limonium bicolor
In the present study, an endochitinase gene, Lbchi32, was cloned from Limonium bicolor. The cDNA sequence of Lbchi32 was 1,443 bp in length and encoded 319 amino acid residues. The DNA sequence of Lbchi32 was 2,5...
-
Article
A glycine-rich RNA-binding protein can mediate physiological responses in transgenic plants under salt stress
Glycine-rich RNA-binding proteins (GRPs) are involved in post-transcriptional regulation of genes, which have been found to play a role in stress response. However, whether GRPs can mediate some physiological ...
-
Article
Circulating miR-130b mediates metabolic crosstalk between fat and muscle in overweight/obesity
Adipose tissue is a dynamic endocrine organ that regulates whole-body energy homeostasis through the secretion of signalling molecules. Recent reports suggest that secreted microRNAs (miRNAs) may function as b...
-
Article
A fuzzy-neural approach for supporting three-objective job scheduling in a wafer fabrication factory
This study is dedicated to three-objective scheduling in a wafer fabrication factory, which has rarely been discussed in the literature but is a very important task. Optimizing a single objective in a complex ...
-
Article
Open AccessRegulation of fatty acid composition and lipid storage by thyroid hormone in mouse liver
Thyroid hormones (THs) are potent hormones modulating liver lipid homeostasis. The perturbation of lipid homeostasis is a hallmark of non-alcoholic fatty liver disease (NAFLD), a very common liver disorder. It...
-
Article
Hepatic miR-378 targets p110α and controls glucose and lipid homeostasis by modulating hepatic insulin signalling
Understanding the regulation of insulin signalling in tissues provides insights into carbohydrate and lipid metabolism in physiology and disease. Here we show that hepatic miR-378/378* expression changes in re...
-
Article
Effects of rapamycin against paraquat-induced pulmonary fibrosis in mice
Ingestion of paraquat (PQ), a widely used herbicide, can cause severe toxicity in humans, leading to a poor survival rate and prognosis. One of the main causes of death by PQ is PQ-induced pulmonary fibrosis, ...
-
Article
Open AccessHypoxia-inducible miR-182 enhances HIF1α signaling via targeting PHD2 and FIH1 in prostate cancer
Activation of hypoxia-inducible factor 1α (HIF1α) controls the transcription of genes governing angiogenesis under hypoxic condition during tumorigenesis. Here we show that hypoxia-responsive miR-182 is regula...
-
Article
Open AccessYAGM: a web tool for mining associated genes in yeast based on diverse biological associations
Investigating association between genes can be used in understanding the relations of genes in biological processes. STRING and GeneMANIA are two well-known web tools which can provide a list of associated gen...
-
Article
Evaluating sustainable advantages in productivity with a systematic procedure
All factories strive to enhance productivity. In addition, in some industries, the competition is becoming fierce. To survive, a firm should have sustainable advantages in productivity. To this end, a systemat...
-
Article
Open AccessmicroRNA and thyroid hormone signaling in cardiac and skeletal muscle
Thyroid hormone (TH) signaling plays critical roles in the differentiation, growth, metabolism, and physiological function of all organs or tissues, including heart and skeletal muscle. Due to the significant ...
-
Article
Open AccessA novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity
Protein kinase B (PknB) is one of the Mycobacterium tuberculosis serine/threonine protein kinases and has an essential role in sustaining mycobacterial growth. Here, we identified and characterized a novel small ...
-
Article
Open AccessSmall molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways
Osteoporosis results from the imbalance between bone resorption and bone formation, and restoring the normal balance of bone remodeling is highly desirable for identification of better treatment. In this study...
-
Article
A fuzzy collaborative intelligence approach for estimating future yield with DRAM as an example
To increase the ecological sustainability of manufacturing, enhancing the yield of each product is a critical task that eliminates waste and increases profitability. An equally crucial task is to estimate the ...
