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  1. No Access

    Article

    Enhanced specific antibody productivity of hybridomas resulting from hyperosmotic stress is cell line-specific

    Hybridomas with non-growth-associated antibody production are thought to exhibit enhanced specific monoclonal antibody productivity (q MAb) when subjected to hyperosmotic stress. Two hybridoma cell lines exhibiti...

    Gyun Min Lee, Sung Young Park in Biotechnology Letters (1995)

  2. No Access

    Article

    Removal of attenuator region of thr operon increases the production of threonine in Escherichia coli

    Expression of the threonine (thr) operon of Escherichia coli is regulated by an attenuation mechanism. The regulatory portion of the thr operon contains a region coding for leader peptide that includes both conse...

    Eun Young Park, Ji Ha Kim, Hyung Hwan Hyun, Hyune Hwan Lee in Biotechnology Letters (2002)

  3. No Access

    Article

    Intracellular drug delivery using poly(d,l-lactide-co-glycolide) nano- particles derivatized with a peptide from a transcriptional activator protein of HIV-1

    Biodegradable poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles were derivatized with Tat49−57 peptide, which is the protein transduction domain from the transcriptional activator Tat protein of human immunodef...

    Yoon Sung Nam, Ju Young Park, Sang-Hoon Han, Ih-Seop Chang in Biotechnology Letters (2002)

  4. No Access

    Article

    Development of 3-D nanofibrous fibroin scaffold with high porosity by electrospinning: implications for bone regeneration

    We made a three-dimensional (3-D) nanofibrous fibroin scaffold (NFS) with high porosity (94%) and examined its feasibility in bone regeneration. Under scanning electron microscopy, MC3T3-E1 preosteoblasts on t...

    Chang Seok Ki, Sook Young Park, Hyun Jeong Kim, Hong-Moon Jung… in Biotechnology Letters (2008)

  5. No Access

    Article

    1,3-Dichloro-2-propanol induces apoptosis via both calcium and ROS in mouse melanoma cells

    We demonstrated that the apoptotic cell death of mouse melanoma cells exposed to 1,3-dichloro-2-propanol (DCP) was Ca2+ dependent. 1,3-DCP inhibited the growth of mouse melanoma cells in a concentration-dependent...

    Sun Young Park, Young Hun Kim, Young Hee Kim, Sang-Joon Lee in Biotechnology Letters (2010)

  6. No Access

    Article

    Development of 3-D poly(trimethylenecarbonate-co-ε-caprolactone)-block-poly(p-dioxanone) scaffold for bone regeneration with high porosity using a wet electrospinning method

    The three dimensional (3-D) poly(trimethylenecarbonate-co-ε-caprolactone)-block-poly(p-dioxanone) scaffold was made using a wet electrospinning method and its application as a tissue engineered matrix was evaluat...

    Teo Jeon Shin, Sook Young Park, Hyun Jeong Kim, Hak Jun Lee… in Biotechnology Letters (2010)

  7. No Access

    Article

    Optimization of enantioselective synthesis of methyl (R)-2-chloromandelate by whole cells of Saccharomyces cerevisiae

    Methyl (R)-2-chloromandelate, a key intermediate in the synthesis of clopidogrel, was obtained by the reduction of methyl-2-chlorobenzoylformate using whole cells of Saccharomyces cerevisiae. A 100% conversion an...

    Min Jeong, Yoon Mi Lee, Soon Ho Hong, Sung Young Park, Ik-keun Yoo… in Biotechnology Letters (2010)

  8. Article

    Application of recombinant hemagglutinin proteins as alternative antigen standards for pandemic influenza vaccines

    The single radial immunodiffusion (SRID) assay, used to quantify hemagglutinin (HA) in influenza vaccines, requires reference reagents; however, because centralized production of reference reagents may slow th...

    Ye** Choi, Seong Yi Kwon, Ho Jung Oh, Sunbo Shim, Seokkee Chang… in Biotechnology Letters (2017)

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  9. Article

    Open Access

    A classical swine fever virus E2 fusion protein produced in plants elicits a neutralizing humoral immune response in mice and pigs

    Classical swine fever (CSF) is one of the most important viral diseases of swine worldwide. Although live or attenuated virus vaccines have been used to control CSFV, it is difficult to distinguish vaccinated ...

    Youngmin Park, Sangmin Lee, Hyangju Kang, Minhee Park… in Biotechnology Letters (2020)

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