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  1. No Access

    Article

    Circulating extracellular vesicles are associated with pathophysiological condition including metabolic syndrome-related dysmetabolism in children and adolescents with obesity

    Obesity of children and adolescents (OCA) is often accompanied by metabolic syndrome (MetS), which often leads to adult obesity and subsequent complications, yet the entire pathophysiological response is not f...

    Yoshinao Kobayashi, Akiko Eguchi, Koshi Imami… in Journal of Molecular Medicine (2024)

  2. No Access

    Article

    Factors contributing to the development of overt encephalopathy in liver cirrhosis patients

    The aim of this study was to clarify the relationships among psychometric testing results, blood ammonia (NH3) levels, electrolyte abnormalities, and degree of inflammation, and their associations with the develo...

    Motoh Iwasa, Ryosuke Sugimoto, Rumi Mifuji-Moroka, Nagisa Hara… in Metabolic Brain Disease (2016)

  3. No Access

    Article

    Regional reduction in gray and white matter volume in brains of cirrhotic patients: voxel-based analysis of MRI

    Chronic hepatic encephalopathy is a characteristically reversible neuropsychiatric disorder that occurs mainly in patients with liver cirrhosis. The brain regions critically involved in the pathophysiology of ...

    Motoh Iwasa, Rumi Mifuji-Moroka, Makoto Kuroda, Hideo Moroka… in Metabolic Brain Disease (2012)

  4. Article

    Open Access

    Hepcidin Expression in the Liver: Relatively Low Level in Patients with Chronic Hepatitis C

    Patients with chronic hepatitis C frequently have serum and hepatic iron overload, but the mechanism is unknown. Recently identified hepcidin, exclusively synthesized in the liver, is thought to be a key regul...

    Naoki Fujita, Ryosuke Sugimoto, Masaki Takeo, Naohito Urawa… in Molecular Medicine (2007)

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