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  1. Article

    Open Access

    Effects of short-term fructooligosaccharide intake on equol production in Japanese postmenopausal women consuming soy isoflavone supplements: a pilot study

    Recent studies suggest that some of the clinical effectiveness of soy or daidzein, which is a type of isoflavone, may be attributed to a person’s ability to produce equol from daidzein. Equol, which is a metab...

    Yuko Tousen, Mariko Uehara, Fumiko Abe, Yoshifumi Kimira in Nutrition Journal (2013)

  2. Article

    Open Access

    Collagen-derived dipeptide prolyl-hydroxyproline promotes osteogenic differentiation through Foxg1

    Prolyl-hydroxyproline (Pro-Hyp) is one of the major constituents of collagen-derived dipeptides. We previously reported that Pro-Hyp promotes the differentiation of osteoblasts by increasing Runx2, osterix and...

    Yoshifumi Kimira, Haruka Odaira, Kaho Nomura in Cellular & Molecular Biology Letters (2017)

  3. Article

    Open Access

    Monitoring urinary collagen metabolite changes following collagen peptide ingestion and physical activity using ELISA with anti active collagen oligopeptide antibody

    Active collagen oligopeptides (ACOP) are bioactive collagen-derived peptides detected by a recently-established ELISA. To facilitate studies of the function and metabolism of these products, this study aims to...

    Yoshihiro Osawa, Kaho Nomura, Yoshifumi Kimira, Seiji Kushibe in Scientific Reports (2021)