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Article
Open AccessSpatial heterogeneity of tumor microenvironment influences the prognosis of clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is an immunologically and histologically diverse tumor. However, how the structural heterogeneity of tumor microenvironment (TME) affects cancer progression and treatmen...
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Article
Open AccessGenomic and transcriptomic features between primary and paired metastatic fumarate hydratase–deficient renal cell carcinoma
Fumarate hydratase–deficient renal cell carcinoma (FH-RCC) is a rare highly aggressive subtype of kidney cancer for which the distinct genomic, transcriptomic, and evolutionary relationships between metastatic...
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Article
Open AccessEfficacy and safety of nonpharmacological strategies for the treatment of oligoasthenospermia: a systematic review and Bayesian network meta-analysis
Oligoasthenospermia (OAT) is the most common cause of male infertility, and the annual incidence of the disease continues to increase due to changing lifestyle habits, increased work pressure and increased env...