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Open AccessHow does the environmental attention of local governments affect regional green development? Empirical evidence from local governments in China
Due to the continuous progress of constructing sustainable environments in China, the role played by the Chinese central government as the main body for promoting green development is worth studying. Because C...
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Article
Open AccessChromosome-level genome assembly of the Japanese sawyer beetle Monochamus alternatus
The Japanese sawyer beetle Monochamus alternatus (Coleoptera: Cerambycidae) is a pest in pine forests and acts as a vector for the pine wood nematode Bursaphelenchus xylophilus, which causes the pine wilt disease...
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Article
Open AccessSeasonally-reversed trends in the subtropical Northwestern Pacific linked to asymmetric AMO influences
This study identifies seasonally-reversed trends in Kuroshio strength and sea surface temperatures (SSTs) within the western North Pacific (WNP) since the 1990s, specifically in the 22° N–28° N region. These t...
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Open AccessIntensified modulation of the Pacific north equatorial current bifurcation by the southern annular mode since the early 1990s
Long-term reanalysis data were used to assess inter-decadal to decadal modulations of the North Equatorial Current (NEC) bifurcation in the Pacific after the early 1990s. The wind stress curl anomaly (WSCA) in...
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Open AccessA solution for the rational dispatching of concrete transport vehicles
The amount of concrete needed in the construction of projects is enormous. The concrete dispatching in construction is, however, chaotic and causes grievous waste due to the tight construction schedule, heavy ...
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Article
Open AccessIn vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis
Given the complex nature of ulcerative colitis, combination therapy targeting multiple pathogenic genes and pathways of ulcerative colitis may be required. Unfortunately, current therapeutic strategies are usu...
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Article
Open AccessOXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling
The Pattern Of Invasion (POI) of tumor cells into adjacent normal tissues clinically predicts postoperative tumor metastasis/recurrence of early oral squamous cell carcinoma (OSCC), but the mechanisms underlyi...
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Open AccessBicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase
Toxoplasma gondii commonly infects humans and while most infections are controlled by the immune response, currently approved drugs are not capable of clearing chronic infection in humans. Hence, approximately on...
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Open AccessPublisher Correction: Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins
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Open AccessEffects of mixed meal tolerance test on gastric emptying, glucose and lipid homeostasis in obese nonhuman primates
Meal ingestion elicits a variety of neuronal, physiological and hormonal responses that differ in healthy, obese or diabetic individuals. The mixed meal tolerance test (MMTT) is a well-established method to ev...
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Open AccessCryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins
In living cells, microtubules (MTs) play pleiotropic roles, which require very different mechanical properties. Unlike the dynamic MTs found in the cytoplasm of metazoan cells, the specialized cortical MTs from T...
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Open AccessImpact of the southern annular mode on extreme changes in indian rainfall during the early 1990s
The variability in rainfall amounts in India draws much attention because it strongly influences the country’s ecological and social systems. Indian rainfall is associated with climate factors, including El Ni...
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Open AccessTensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement
Orthodontic force-induced osteogenic differentiation and bone formation at tension side play a pivotal role in orthodontic tooth movement (OTM). Platelet-derived growth factor-BB (PDGF-BB) is a clinically prov...
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Open AccessAuthor Correction: Urinary metabolic variation analysis during pregnancy and application in Gestational Diabetes Mellitus and spontaneous abortion biomarker discovery
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessAn Atlantic-driven rapid circulation change in the North Pacific Ocean during the late 1990s
Interbasin interactions have been increasingly emphasized in recent years due to their roles in sha** climate trends and the global warming hiatus in the northern hemisphere. The profound influence from the ...
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Open AccessFungal dissemination is limited by liver macrophage filtration of the blood
Fungal dissemination into the bloodstream is a critical step leading to invasive fungal infections. Here, using intravital imaging, we show that Kupffer cells (KCs) in the liver have a prominent function in th...
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Open AccessCoherent Response of Vietnam and Sumatra-Java Upwellings to Cross-Equatorial Winds
Upwelling off Vietnam in the South China Sea (SCS) and the Sumatra–Java upwelling in the Indian Ocean significantly modulate regional variation in climate. Although located in different hemispheres, these upwe...
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Open AccessUrinary metabolic variation analysis during pregnancy and application in Gestational Diabetes Mellitus and spontaneous abortion biomarker discovery
Pregnancy is associated with the onset of many adaptation processes that are likely to change over the course of gestation. Understanding normal metabolites’ variation with pregnancy progression is crucial for...
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Open AccessImpact of the Atlantic Multidecadal Oscillation on the Pacific North Equatorial Current bifurcation
Variability in surface currents is mainly induced by the time-varying wind forcing. Recent studies have revealed robust pronounced changes in the atmospheric circulation over the Pacific came with the Pacific ...
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Open AccessDistinct impacts of the 1997–98 and 2015–16 extreme El Niños on Japanese eel larval catch
Extraordinarily poor recruitment of Japanese eels in East Asia has been generally reported during extreme El Niño years. However, the scenario failed to take place during the 2015–16 extreme event. In this stu...