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  1. Article

    IL-3 and CTLA4 gene polymorphisms may influence the tacrolimus dose requirement in Chinese kidney transplant recipients

    The highly variable pharmacokinetics and narrow therapeutic window of tacrolimus (TAC) has hampered its clinical use. Genetic polymorphisms may contribute to the variable response, but the evidence is not comp...

    Mou-ze Liu, Hai-yan He, Yue-li Zhang, Yong-fang Hu in Acta Pharmacologica Sinica (2017)