1,597 Result(s)
within
Yong-**an Fan
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Article
Decreased retinal vascular density is associated with cognitive impairment in CADASIL: an optical coherence tomography angiography study
This study aimed to assess alterations in retinal vascular density in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) patients using optical coherence tomog...
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PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Synchronized ferroptosis contributes to nephron loss in acute kidney injury (AKI). However, the propagation signals and the underlying mechanisms of the synchronized ferroptosis for renal tubular injury remain...
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Microstructures and mechanical properties of laser-directed energy deposited CrCoNi medium-entropy alloy
The distinctive intrinsic heat treatment (IHT) originating from cyclic reheating in the laser-directed energy deposition (LDED) has attracted growing attention in recent years. In this investigation, simulatio...
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Improvement in corrosion resistance of Mg97Zn1Y2 alloy by Zr addition
Magnesium alloys, known for their exceptional lightweight properties, have presented challenges in various applications due to their limited corrosion resistance. In this study, the corrosion resistance of Mg97Zn
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Open AccessMobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma
Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma (ICC). However, it remains elusive how ICC cells subvert immu...
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Open AccessExploring the biogeography, morphology, and phylogeny of the condylostomatid ciliates (Alveolata, Ciliophora, Heterotrichea), with establishment of four new Condylostoma species and a revision including redescriptions of five species found in China
Species of the ciliate class Heterotrichea Stein, 1859 are a cosmopolitan group of unicellular eukaryotic microorganisms, many of which have been widely used as models in various fields of research such as reg...
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Open AccessAdvances in the Treatment of Neuropathic Pain by Sympathetic Regulation
To explore the mechanism and therapeutic effect of sympathetic nerve regulation on neuropathic pain.
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Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities
With the advancement of modern science and technology, large scientific facilities are increasingly oriented toward demand and application, and can be used for basic research as well as serving multiple discip...
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Open AccessAdvances in spatial transcriptomics and its applications in cancer research
Malignant tumors have increasing morbidity and high mortality, and their occurrence and development is a complicate process. The development of sequencing technologies enabled us to gain a better understanding...
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Effects of particle size and oil-immersed concentration on the dust layer minimum ignition temperature and combustion characteristics of oil-immersed coal
This paper studied the minimum ignition temperature of the dust layer (MITL) of oil-immersed coal and the heat effect and apparent activation energy (Ea) of raw coal and oil-immersed coal. Based upon the results,...
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Open AccessRemodeling of anti-tumor immunity with antibodies targeting a p53 mutant
p53, the most frequently mutated gene in cancer, lacks effective targeted drugs.
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Open AccessInhibiting the CB1 receptor in CIH-induced animal model alleviates colon injury
Obstructive sleep apnea (OSA) can lead to intestinal injury, endotoxemia, and disturbance of intestinal flora. Additionally, as a crucial component of the endocannabinoid system, some studies have demonstrated...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessHigh performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants
Cytosine base editors (CBEs) and adenine base editors (ABEs) enable precise C-to-T and A-to-G edits. Recently, ABE8e, derived from TadA-8e, enhances A-to-G edits in mammalian cells and plants. Interestingly, T...
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Open AccessAssociation between indicators of visceral lipid accumulation and infertility: a cross-sectional study based on U.S. women
Evidence on the association between visceral lipid accumulation and infertility remains limited and controversial. Therefore, the current investigation is the first investigation to unveil this correlation by ...
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Sustainably releasing osteogenic trace elements from montmorillonite intercalated hybrid nanocomposites accelerates bone regeneration
Optimizing scaffold components and architectures to achieve endogenous osteogenesis is a prospective advancement for bone tissue engineering. Here, montmorillonite was introduced as a reinforcing phase into a ...
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Open AccessRadiomics of pericoronary adipose tissue on computed tomography angiography predicts coronary heart disease in patients with type 2 diabetes mellitus
Diabetes is a common chronic metabolic disease. The progression of the disease promotes vascular inflammation and the formation of atherosclerosis, leading to cardiovascular disease. The coronary artery periva...
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Open AccessGenome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers
Dysregulation of enhancer transcription occurs in multiple cancers. Enhancer RNAs (eRNAs) are transcribed products from enhancers that play critical roles in transcriptional control. Characterizing the genetic...
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Experimental quantum computational chemistry with optimized unitary coupled cluster ansatz
Quantum computational chemistry has emerged as a potential application of quantum computing. Hybrid quantum-classical computing methods, such as variational quantum eigensolvers, have been designed as promisin...
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Analysis of mild and severe neonatal enterovirus infections in a Chinese neonatal tertiary center: a retrospective case-control study
To compare the clinical characteristics, virus serotype, and outcome in cases of mild and severe enteroviral infection at a tertiary neonatal intensive care unit in China.
