11 Result(s)

Article

Targeting the SOX2/CDP protein complex with a peptide suppresses the malignant progression of esophageal squamous cell carcinoma

Emerging evidence indicates that SOX2 is an oncogene for esophageal squamous cell carcinoma (ESCC). However, direct targeting of SOX2 is not feasible given that this transcription factor plays important roles ...

Yunyun Chen, Kun Zhang, Rui Zhang, Zhuo Wang, Liang Yang… in Cell Death Discovery (2023)

Article

MicroRNA-148a-3p suppresses cell proliferation and migration of esophageal carcinoma by targeting CEP55

This study evaluated microRNA-148a-3p in esophageal carcinoma cells. The prediction of bioinformatics analysis revealed that microRNA-148a-3p may target CEP55. qRT-PCR and western blot showed that CEP55 level ...

Yong Lin, Yushan Chen, Rongqiang Shen, Dingzhu Chen… in Cellular & Molecular Biology Letters (2021)

Article

Over-expression of lncRNA TMEM161B-AS1 promotes the malignant biological behavior of glioma cells and the resistance to temozolomide via up-regulating the expression of multiple ferroptosis-related genes by sponging hsa-miR-27a-3p

A growing body of evidence suggests that long-chain non-coding RNA (lncRNA) plays an important role in the malignant biological behavior and drug resistance of glioblastoma (GBM) cells. In this study, we analy...

Qiudan Chen, Weifeng Wang, Zhong Wu, Shuying Chen, **aotong Chen… in Cell Death Discovery (2021)

Article

miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop

Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signal...

Qiudan Chen, Weifeng Wang, Shuying Chen… in Cellular & Molecular Biology Letters (2021)

Article

The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the ongoing coronavirus disease 2019 pandemic. How SARS-CoV-2 regulates cellular responses to escape clearance by host cells is unknown. ...

Yabin Zhang, Hao Sun, Rongjuan Pei, Binli Mao, Zhenyu Zhao, Huihui Li… in Cell Discovery (2021)

Article

Identification of a quantitative trait loci (QTL) associated with ammonia tolerance in the Pacific white shrimp (Litopenaeus vannamei)

Ammonia is one of the most common toxicological environment factors affecting shrimp health. Although ammonia tolerance in shrimp is closely related to successful industrial production, few genetic studies of ...

Digang Zeng, Chunling Yang, Qiangyong Li, Weilin Zhu, **uli Chen, Min Peng… in BMC Genomics (2020)

Article

Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components

Yong Lin, Chunchen Wu, Xueyu Wang, Thekla Kemper, Anthony Squire… in Protein & Cell (2019)

Article

Proteomic analysis of the inhibitory effect of epigallocatechin gallate on lipid accumulation in human HepG2 cells

(−)-Epigallocatechin-3-gallate (EGCG), the most abundant catechin found in green tea, effectively reduces body weight and tissue and blood lipid accumulation. To explore the mechanism by which EGCG inhibits ce...

Zhonghua Liu, Qin Li, Jianan Huang, Qionglin Liang, Yujun Yan… in Proteome Science (2013)

Article

Enrichment and proteomic analysis of plasma membrane from rat dorsal root ganglions

Dorsal root ganglion (DRG) neurons are primary sensory neurons that conduct neuronal impulses related to pain, touch and temperature senses. Plasma membrane (PM) of DRG cells plays important roles in their fun...

**a **ong, Sha Huang, Hai Zhang, Jianjun Li, Jianying Shen… in Proteome Science (2009)

Article

Rapid detection and curation of conserved DNA via enhanced-BLAT and EvoPrinterHD analysis

Multi-genome comparative analysis has yielded important insights into the molecular details of gene regulation. We have developed EvoPrinter, a web-accessed genomics tool that provides a single uninterrupted view...

Amarendra S Yavatkar, Yong Lin, Jermaine Ross, Yang Fann, Thomas Brody… in BMC Genomics (2008)

Article

Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP)

RMP was reported to regulate transcription via competing with HBx to bind the general transcription factor IIB (TFIIB) and interacting with RPB5 subunit of RNA polymerase II as a corepressor of transcription r...

Wenxiang WEI, Jun **a GU, Cui Qing ZHU, Feng Yan SUN, Dorjbal DORJSUREN… in Cell Research (2003)