4 Result(s)
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Article
Open AccessMicroRNA-148a-3p suppresses cell proliferation and migration of esophageal carcinoma by targeting CEP55
This study evaluated microRNA-148a-3p in esophageal carcinoma cells. The prediction of bioinformatics analysis revealed that microRNA-148a-3p may target CEP55. qRT-PCR and western blot showed that CEP55 level ...
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Article
Open AccessmiR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop
Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signal...
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Article
QSAR Study on Insect Neuropeptide Potencies Based on a Novel Set of Parameters of Amino Acids by Using OSC-PLS Method
The potencies of natural adipokinetic hormones and synthetic variants (short peptides) have been obtained in Locusta migratoria. This short peptides (a total of sixty-nine analogues) data was used to construct th...
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Article
Quantitative Structure–Activity Relationship Model for Prediction of Protein–Peptide Interaction Binding Affinities between Human Amphiphysin-1 SH3 Domains and Their Peptide Ligands
Protein–protein interaction plays a critical role in signal transduction and many other key biological processes. The present study evaluated four parameters selected from among 554 physiochemical variables of...
