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    Article

    Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts

    Oxidative stress plays a critical role in cardiac injury during ischemia/reperfusion (I/R). Despite a potent cardioprotective activity of KR-33889, a novel poly (ADP-ribose) polymerase inhibitor, its underlyin...

    Eun-Seok Park, Do-Hyun Kang, Jun Chul Kang in Archives of Pharmacal Research (2017)

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    Article

    Cordycepin, 3′-Deoxyadenosine, Prevents Rat Hearts from Ischemia/Reperfusion Injury Via Activation of Akt/GSK-3β/p70S6K Signaling Pathway and HO-1 Expression

    Cordycepin (3′-deoxyadenosine) isolated from Cordyceps militaris, a species of the fungal genus Cordyceps, has been shown to exhibit many pharmacological functions, such as anticancer, anti-inflammatory, and anti...

    Eun-Seok Park, Do-Hyun Kang, Min-Kyu Yang, Jun Chul Kang in Cardiovascular Toxicology (2014)