8 Result(s)

Article

Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation

Observational studies suggest that abnormal glucose metabolism and insulin resistance contribute to colorectal cancer; however, the causal association remains unknown, particularly in Asian populations. A two-...

Akiko Hanyuda, Atsushi Goto, Ryoko Katagiri, Yuriko N. Koyanagi… in Scientific Reports (2023)

Article

Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba… in Nature (2022)

Article

Stroke genetics informs drug discovery and risk prediction across ancestries

Previous genome-wide association studies (GWASs) of stroke — the second leading cause of death worldwide — were conducted predominantly in populations of European ancestry^1,2. Here, in cross-ancestry GWAS meta-an...

Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba… in Nature (2022)

Article

Author Correction: Elephant shark genome provides unique insights into gnathostome evolution

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Byrappa Venkatesh, Alison P. Lee, Vydianathan Ravi, Ashish K. Maurya… in Nature (2020)

Article

ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis

Liver tests (LT), especially to measure AST, ALT and GGT levels, are widely used to evaluate the risk of alcohol-related liver disease (ALD). In this study, we investigated the potential genetic factors that m...

Yoichi Sutoh, Tsuyoshi Hachiya, Yuji Suzuki, Shohei Komaki… in Scientific Reports (2020)

Article

Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3′-BCL11B gene desert locus

Excessive sodium intake is a global risk factor for hypertension. Sodium effects on blood pressure vary from person to person; hence, high-risk group targeting based on personal genetic information can play a ...

Tsuyoshi Hachiya, Akira Narita, Hideki Ohmomo, Yoichi Sutoh… in Scientific Reports (2018)

Article

Correction: Corrigendum: Elephant shark genome provides unique insights into gnathostome evolution

Nature 505, 174–179 (2014); doi:10.1038/nature12826 The ranges of accession numbers JW861113–JW881738 and KA353634–KA353668 (20,661 in total) cited in this Article include 3,630 sequences that were unrelated a...

Byrappa Venkatesh, Alison P. Lee, Vydianathan Ravi, Ashish K. Maurya… in Nature (2014)

Article

Elephant shark genome provides unique insights into gnathostome evolution

The emergence of jawed vertebrates (gnathostomes) from jawless vertebrates was accompanied by major morphological and physiological innovations, such as hinged jaws, paired fins and immunoglobulin-based adapti...

Byrappa Venkatesh, Alison P. Lee, Vydianathan Ravi, Ashish K. Maurya… in Nature (2014)