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  1. Article

    Open Access

    The Neo-PLANET phase II trial of neoadjuvant camrelizumab plus concurrent chemoradiotherapy in locally advanced adenocarcinoma of stomach or gastroesophageal junction

    The synergistic effect of neoadjuvant immunotherapy and chemoradiotherapy in gastric adenocarcinoma is unclear. This phase II trial (NCT03631615) investigated this neoadjuvant combination in locally advanced a...

    Zhaoqing Tang, Yan Wang, Dan Liu, Xuefei Wang, Chen Xu, Yiyi Yu in Nature Communications (2022)

  2. Article

    Open Access

    Multiplexed nanomaterial-assisted laser desorption/ionization for pan-cancer diagnosis and classification

    As cancer is increasingly considered a metabolic disorder, it is postulated that serum metabolite profiling can be a viable approach for detecting the presence of cancer. By multiplexing mass spectrometry fing...

    Hua Zhang, Lin Zhao, **g**g Jiang, Jie Zheng, Li Yang, Yanyan Li in Nature Communications (2022)

  3. Article

    Open Access

    Diesel2p mesoscope with dual independent scan engines for flexible capture of dynamics in distributed neural circuitry

    Imaging the activity of neurons that are widely distributed across brain regions deep in scattering tissue at high speed remains challenging. Here, we introduce an open-source system with Dual Independent Enha...

    Che-Hang Yu, Jeffrey N. Stirman, Yiyi Yu, Riichiro Hira in Nature Communications (2021)

  4. Article

    Open Access

    Stimulus-specific regulation of visual oddball differentiation in posterior parietal cortex

    The frequency at which a stimulus is presented determines how it is interpreted. For example, a repeated image may be of less interest than an image that violates the prior sequence. This process involves inte...

    Zhe Charles Zhou, Wei Angel Huang, Yiyi Yu, Ehsan Negahbani in Scientific Reports (2020)

  5. Article

    Open Access

    Mice use robust and common strategies to discriminate natural scenes

    Mice use vision to navigate and avoid predators in natural environments. However, their visual systems are compact compared to other mammals, and it is unclear how well mice can discriminate ethologically rele...

    Yiyi Yu, Riichiro Hira, Jeffrey N. Stirman, Waylin Yu, Ikuko T. Smith in Scientific Reports (2018)

  6. Article

    Open Access

    Inner membrane fusion mediates spatial distribution of axonal mitochondria

    In eukaryotic cells, mitochondria form a dynamic interconnected network to respond to changing needs at different subcellular locations. A fundamental yet unanswered question regarding this network is whether ...

    Yiyi Yu, Hao-Chih Lee, Kuan-Chieh Chen, Joseph Suhan, Minhua Qiu in Scientific Reports (2016)