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Article
A high efficient sorption of U(VI) from aqueous solution using amino-functionalized SBA-15
Uranium is one of the most hazardous heavy metal due to its long half-life radioactivity, high toxicity and mobility as aqueous uranyl ion (UO2 2+) under ordinary environmental conditions. Herein,...
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Article
Mesoporous silica SBA-15 functionalized with phosphonate and amino groups for uranium uptake
Mesoporous silicas have a very attractive ability of sorption and enrichment of metal ions due to their huge surface area and facile functionalization by organic ligands. In this work, phosphonate-amino bifunc...
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Article
Interactions between U(VI) and bovine serum albumin
Interest in bio-toxicology of uranium resulting from its radioactive heavy metal property has been growing enormously in recent years. The interactions between uranium(VI) [U(VI)] and bovine serum albumin (BSA...
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Article
Open AccessThe novel 19q13 KRAB zinc-finger tumour suppressor ZNF382 is frequently methylated in oesophageal squamous cell carcinoma and antagonises Wnt/β-catenin signalling
Zinc finger proteins (ZFPs) are the largest transcription factor family in mammals. About one-third of ZFPs are Krüppel-associated box domain (KRAB)-ZFPs and involved in the regulation of cell differentiation/...
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Article
Open AccessA blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model
Chronic kidney disease (CKD) poses a formidable challenge for public healthcare worldwide as vast majority of patients with CKD are also at risk of accelerated cardiovascular disease and death. Renal fibrosis ...
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Article
Open AccessThe epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism
Recent studies suggested the globin family member cytoglobin (CYGB) as a potential tumor suppressor; however, the mechanism by which CYGB suppresses cancer is elusive. We investigated the role and mechanism of...
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Article
Open AccessMonensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway
Pancreatic ductal adenocarcinoma (PDAC) is one of the most deadly malignancies with <5% five-year survival rate due to late diagnosis, limited treatment options and chemoresistance. There is thus an urgent unm...
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Article
Open AccessZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer
Recent studies suggested that ZMYND10 is a potential tumor suppressor gene in multiple tumor types. However, the mechanism by which ZMYND10 inhibits breast cancer remains unclear. Here, we investigated the role a...
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Article
Open AccessA simplified system for the effective expression and delivery of functional mature microRNAs in mammalian cells
MicroRNAs (miRNAs) are ~22 nucleotide noncoding RNAs that are involved in virtually all aspects of cellular process as their deregulations are associated with many pathological conditions. Mature miRNAs (mMIRs...
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Article
Open AccessCancer cells escape p53’s tumor suppression through ablation of ZDHHC1-mediated p53 palmitoylation
The inactivation of tumor-suppressor genes contributes heavily to oncogenesis. The mutation of TP53 has been well-studied and recognized as a major factor in the development of tumors. Yet other means of p53 i...
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Article
Open AccessCorrection to: ZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer
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Chapter and Conference Paper
Design of a Visual Guidance Robotic Assembly System for Flexible Satellite Equipment Unit Assembly
The growing demand for small satellite manufacturing has stimulated the need for automated assembly of satellite equipment units. The assembly process requires flexibility, characteristic of space assembly whi...
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Chapter and Conference Paper
Kinematic Calibration of a 2-DOF Over-Constrained Parallel Manipulator Using Force Data
The over-constrained parallel manipulators have drawn a lot of attention, and their application potential is constantly being explored. To improve the performance of the over-constrained mechanism, the actual ...
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Chapter and Conference Paper
Torque Ripple Analysis and Model of Symmetrical Six-Phase Fault-Tolerant PMSM
This paper focuses on the torque ripple analysis of interior permanent magnet synchronous motor equipped with fractional slot concentrated winding under fault conditions. When the motor suffers from faults, to...
