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1,432 Result(s)
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Article
Open AccessInhibition of autophagy induced by tetrandrine promotes the accumulation of reactive oxygen species and sensitizes efficacy of tetrandrine in pancreatic cancer
Pancreatic cancer, characterized by its poor prognosis, exhibits a marked resistance to conventional chemotherapy and immunotherapy, underscoring the urgent need for more effective treatment modalities. In lig...
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Open AccessUnderstanding pedestrian movement using urban sensing technologies: the promise of audio-based sensors
While various sensors have been deployed to monitor vehicular flows, sensing pedestrian movement is still nascent. Yet walking is a significant mode of travel in many cities, especially those in Europe, Africa...
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Open AccessDoes bilateral Wilms’ tumor involving the collecting system in children have a worse prognosis?
The literature on nephron-sparing surgery (NSS) in children with bilateral Wilms’ tumors (BWT) involving the collection system is mostly comprised of case reports. The present study aimed to summarize the clin...
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Measuring spot sizes of laser-excited phosphor ceramics with a goniophotometer
In packaging processes of laser lighting sources, the matching degree between excited laser spots and the sizes of phosphor conversion materials directly affects light efficiency of packaged light sources. The...
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Impact of Adult Children’s Socioeconomic Status on the Health of Older Adults in China
Improving the health of older adults is a crucial response to population aging. Based on the China Family Panel Studies data, this study analyzes the relationship between the children’s socioeconomic status an...
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Open AccessBiotin-modified mesoporous silica nanoparticles as a delivery system for quercetin and gallic acid for bacterial biofilm eradication
The effective management of biofilm-associated infections remains a pressing concern in clinical practice, necessitating the development of efficient eradication strategies. This study introduces biotin-modifi...
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Open AccessGenetic evidence for causal association between migraine and dementia: a mendelian randomization study
There is an association between migraine and dementia, however, their causal relationship remains unclear. This study employed bidirectional two-sample Mendelian randomization (MR) to investigate the potential...
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Adaptive Beamformer in Hybrid Massive MIMO Using Reconstructed Spatial Covariance Matrix
In order to compensate for high path loss, massive multiple-input multiple-output (MIMO) has been adopted in wireless communication systems operating at millimeter-wave (mmWave) bands. In particular, analog be...
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Open AccessA single-cell chromatin accessibility dataset of human primed and naïve pluripotent stem cell-derived teratoma
Teratoma, due to its remarkable ability to differentiate into multiple cell lineages, is a valuable model for studying human embryonic development. The similarity of the gene expression and chromatin accessibi...
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Open AccessMaternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes
Oocyte in vitro maturation is a technique in assisted reproductive technology. Thousands of genes show abnormally high expression in in vitro maturated metaphase II (MII) oocytes compared to those matured in v...
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Extremal regular graphs and hypergraphs related to fractional repetition codes
Fractional repetition codes (FRCs) are a special family of storage codes with the repair-by-transfer property in distributed storage systems. Constructions of FRCs are naturally related to combinatorial design...
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High-throughput and proteome-wide discovery of endogenous biomolecular condensates
Phase separation inside mammalian cells regulates the formation of the biomolecular condensates that are related to gene expression, signalling, development and disease. However, a large population of endogeno...
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Numerical simulation and experimental study of valveless piezoelectric mixing pump with built-in obstacles
Micro-mixers and piezoelectric pumps have been studied as independent parts, which achieves only single mixing or pum** functions. A new valveless piezoelectric mixing pump (VPMP) driven by a sinusoidal sign...
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Current status and future directions in pediatric ventricular assist device
A ventricular assist device (VAD) is a form of mechanical circulatory support that uses a mechanical pump to partially or fully take over the function of a failed heart. In recent decades, the VAD has become a...
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A study on construction of a prognosis model for liver cancer based on analgesic targets and screening therapeutic drugs
Liver cancer is one of the most malignant liver diseases in the world, and the 5-year survival rate of such patients is low. Analgesics are often used to cure pain prevalent in liver cancer. The expression cha...
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Risk factors of neonatal stroke from different origins: a systematic review and meta-analysis
Given the persistent ambiguity regarding the etiology of neonatal stroke across diverse origins, our objective was to conduct a comprehensive evaluation of both qualitative and quantitative risk factors. An ex...
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Open AccessSirt1 inhibits macrophage polarization and inflammation in gouty arthritis by inhibiting the MAPK/NF-κB/AP-1 pathway and activating the Nrf2/HO-1 pathway
To elucidate Sirt1’s role in gouty arthritis inflammation and its potential mechanisms.
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Design, bioactivity and mechanism of N′-phenyl pyridylcarbohydrazides with broad-spectrum antifungal activity
Succinate dehydrogenase inhibitors (SDHIs) as one of the fastest-growing fungicide categories for plant protection. In this study, a series of N′-phenyl pyridylcarbohydrazides as analogues of commercial SDHIs wer...
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Impacts of Internet Information Literacy on Farmers’ Relative Poverty Vulnerability: Evidence from CGSS Survey Data in China
Alleviating the farmers’ relative poverty promotes social stability. Improving farmers’ Internet information literacy is an important measure to alleviate relative poverty in rural China by fostering farmers’ ...
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Detection methods for antibiotics in wastewater: a review
Antibiotics are widely used as fungicides because of their antibacterial and bactericidal effects. However, it is necessary to control their dosage. If the amount of antbiotics is too much, it cannot be comple...