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  1. No Access

    Article

    Effects of Acupuncture on Glycometabolic Enzymes in Multi-infarct Dementia Rats

    Acupuncture has exhibited therapeutic effects on vascular dementia in our previous research. The mechanism of its anti-dementia effects involves energy metabolism. For brain cells, glucose metabolism is almost...

    Lan Zhao, Peng Shen, Yingying Han, Xuezhu Zhang, Kun Nie… in Neurochemical Research (2011)

  2. No Access

    Article

    miR-124 Represses ROCK1 Expression to Promote Neurite Elongation Through Activation of the PI3K/Akt Signal Pathway

    Recent studies have demonstrated an important role for miR-124, the most abundant and well-conserved brain-specific microRNA(miRNA), in promoting neurite outgrowth and elongation during neuronal differentiatio...

    ** Gu, Siying Meng, Shuhu Liu, Chunhong Jia… in Journal of Molecular Neuroscience (2014)

  3. No Access

    Article

    Inhibition of Transglutaminase Exacerbates Polyglutamine-Induced Neurotoxicity by Increasing the Aggregation of Mutant Ataxin-3 in an SCA3 Drosophila Model

    Transglutaminases (TGs) comprise a family of Ca2+-dependent enzymes that catalyze protein cross-linking, which include nine family members in humans but only a single homolog in Drosophila with three conserved do...

    Yunting Lin, Hua He, Yingying Luo, Ting Zhu, Ranhui Duan in Neurotoxicity Research (2015)

  4. No Access

    Article

    Generation of Human Embryonic Stem Cell Line Expressing zsGreen in Cholinergic Neurons Using CRISPR/Cas9 System

    Lineage specific human embryonic stem cell (hESC) reporter cell line is a versatile tool for biological studies on real time monitoring of differentiation, physiological and biochemical features of special cel...

    **g Zhou, Chencheng Wang, Kunshan Zhang, Yingying Wang, … in Neurochemical Research (2016)

  5. No Access

    Article

    Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism

    The antinociceptive effects of spirocyclopiperazinium salt compound DXL-A-24 on neuropathic pain and chemical-stimulated pain were investigated in this study. After the administration of DXL-A-24, the paw with...

    Ding Wang, Hua Yang, Yingying Liang, **n Wang, **aolei Du… in Neurochemical Research (2019)

  6. No Access

    Article

    HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway

    Paraquat (PQ), a widely characterized neurotoxicant, has been generally accepted as one of the environmental factors in the etiology of Parkinson’s disease (PD). Despite the direct evidence that PQ could induc...

    Min Huang, Muzhen Guo, Kai Wang, Kexin Wu, Yingying Li, Tian Tian… in Neurotoxicity Research (2020)

  7. No Access

    Article

    Transplantation of IFN-γ Primed hUCMSCs Significantly Improved Outcomes of Experimental Autoimmune Encephalomyelitis in a Mouse Model

    The aim of this study was to investigate potential therapeutic effects of IFN-γ primed human umbilical cord mesenchymal stem cell (IFN-γ-hUCMSCs) transplantation on experimental autoimmune encephalomyelitis (E...

    **aoyan Zhou, **aoli Liu, Li Liu, Chao Han, Zhaohong **e… in Neurochemical Research (2020)

  8. No Access

    Article

    Association Between Stroke and Parkinson’s Disease: a Meta-analysis

    Parkinson’s disease (PD) and stroke are both associated with aging, but the relationship between these two disorders remains unclear. Recent evidence has shown that they frequently co-occur and are influenced ...

    Yumei Liu, Li Xue, Yingying Zhang, Anmu **e in Journal of Molecular Neuroscience (2020)

  9. No Access

    Article

    Knockdown of TLR4 Represses the Paraquat-Induced Neuroinflammation and Microglial M1 Polarization

    Paraquat (PQ) is associated with multiple nervous system disorders including Parkinson’s disease. Despite the evidence that PQ could induce inflammatory responses in the central nervous system and largely cont...

    Min Huang, Yingying Li, Tian Tian, Kai Wang, Yifan Wang… in Neurotoxicity Research (2020)

  10. No Access

    Article

    Hypermethylation of Mitochondrial Cytochrome b and Cytochrome c Oxidase II Genes with Decreased Mitochondrial DNA Copy Numbers in the APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease

    Alzheimer’s disease (AD) is the most common cause of dementia. Increasing evidence shows that mitochondrial DNA (mtDNA) methylation plays an essential role in many diseases related to mitochondrial dysfunction...

    Yingying Xu, Ling Cheng, **g Sun, Fan Li, **angtian Liu, Yan Wei… in Neurochemical Research (2021)

  11. No Access

    Article

    Isorhynchophylline Relieves Ferroptosis-Induced Nerve Damage after Intracerebral Hemorrhage Via miR-122-5p/TP53/SLC7A11 Pathway

    Isorhynchophylline (IRN), a component of traditional Chinese herb Uncaria rhynchophylla, possesses strong antioxidant activity. Ferroptosis induced by iron overload causes cell oxidative stress after intracerebra...

    Haikang Zhao, **aoqiang Li, Lei Yang, Liang Zhang, **aobing Jiang… in Neurochemical Research (2021)

  12. Article

    Correction to: Association Study Between Genetic Variation in Whole Mitochondrial Genome and Ischemic Stroke

    A correction to this paper has been published: https://doi.org/10.1007/s12031-021-01833-7

    Yingying Luan, Dongzhi Yang, Zhao**g Zhang… in Journal of Molecular Neuroscience (2021)

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  13. No Access

    Article

    Association Study Between Genetic Variation in Whole Mitochondrial Genome and Ischemic Stroke

    Mitochondrial DNA (mtDNA) affects the mitochondrial function, which is potentially related to susceptibility to ischemic stroke (IS). However, study on IS genetics by whole mitochondrial genome sequencing has ...

    Yingying Luan, Dongzhi Yang, Zhao**g Zhang… in Journal of Molecular Neuroscience (2021)

  14. No Access

    Article

    Activation of PI3k/Akt/mTOR Signaling Induces Deposition of p-tau to Promote Aluminum Neurotoxicity

    Aluminum neurotoxicity impairs learning and memory ability, but the molecular mechanism has not been elucidated. The aim of this study was to examine the role of phosphatidylinositol 3-kinase (PI3K)/Akt/mammal...

    Yirong Xu, Guangheng Zhang, Yingying Zhao, Fan Bu, Ye** Zhang in Neurotoxicity Research (2022)

  15. No Access

    Article

    Effects of Multiple High-Dose Methamphetamine Administration on Enteric Dopaminergic Neurons and Intestinal Motility in the Rat Model

    Several studies have identified the effects of methamphetamine (MA) on central dopaminergic neurons, but its effects on enteric dopaminergic neurons (EDNs) are unclear. The aim of this study was to investigate...

    Li He, Huihui Zheng, Jilong Qiu, Hong Chen, Huan Li, Yuejiao Ma… in Neurotoxicity Research (2023)

  16. No Access

    Article

    AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice

    There is growing evidence showing that adiponectin (APN) can improve Alzheimer’s disease(AD)-like pathological changes by improving insulin resistance. However, the role of AdipoRon (an Adiponectin receptor ag...

    Wenyan Zhao, Wei Zhang, Yingying Hu, Yuliang Zhou, **ying Zhao… in Neurochemical Research (2024)