Skip to main content

12 Result(s)

within Yingying **ao Remove this filter Biomedicine Remove this filter Biochemistry, general Remove this filter Cell Biology Remove this filter

and

  1. No Access

    Article

    AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice

    There is growing evidence showing that adiponectin (APN) can improve Alzheimer’s disease(AD)-like pathological changes by improving insulin resistance. However, the role of AdipoRon (an Adiponectin receptor ag...

    Wenyan Zhao, Wei Zhang, Yingying Hu, Yuliang Zhou, **ying Zhao… in Neurochemical Research (2024)

  2. No Access

    Article

    PLAC8 contributes to the malignant behaviors of cervical cancer cells by activating the SOX4-mediated AKT pathway

    Cervical cancer (CC) is the primary cancer-related cause of morbidity and mortality in women. Previous studies have shown that placenta-specific 8 (PLAC8) has different functions in multiple malignancies. This...

    Boya Deng, Siyang Zhang, Yingying Zhou, Ying Zhu… in Histochemistry and Cell Biology (2023)

  3. No Access

    Article

    CACNA1C-AS2 inhibits cell proliferation and suppresses cell migration and invasion via targeting FBXO45 and PI3K/AKT/mTOR pathways in glioma

    Glioma is the most common brain cancer with a poor prognosis, and its underlying molecular mechanisms still needs to be further explored. In the current study, we discovered that an antisense lncRNA, CACNA1C-A...

    Tong Cao, Yue Cui, Yingying Wang, Linhui Wu, Ke Yu, Kai Chen, Jun **a… in Apoptosis (2022)

  4. No Access

    Article

    Isorhynchophylline Relieves Ferroptosis-Induced Nerve Damage after Intracerebral Hemorrhage Via miR-122-5p/TP53/SLC7A11 Pathway

    Isorhynchophylline (IRN), a component of traditional Chinese herb Uncaria rhynchophylla, possesses strong antioxidant activity. Ferroptosis induced by iron overload causes cell oxidative stress after intracerebra...

    Haikang Zhao, **aoqiang Li, Lei Yang, Liang Zhang, **aobing Jiang… in Neurochemical Research (2021)

  5. No Access

    Article

    Hypermethylation of Mitochondrial Cytochrome b and Cytochrome c Oxidase II Genes with Decreased Mitochondrial DNA Copy Numbers in the APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease

    Alzheimer’s disease (AD) is the most common cause of dementia. Increasing evidence shows that mitochondrial DNA (mtDNA) methylation plays an essential role in many diseases related to mitochondrial dysfunction...

    Yingying Xu, Ling Cheng, **g Sun, Fan Li, **angtian Liu, Yan Wei… in Neurochemical Research (2021)

  6. No Access

    Article

    Transplantation of IFN-γ Primed hUCMSCs Significantly Improved Outcomes of Experimental Autoimmune Encephalomyelitis in a Mouse Model

    The aim of this study was to investigate potential therapeutic effects of IFN-γ primed human umbilical cord mesenchymal stem cell (IFN-γ-hUCMSCs) transplantation on experimental autoimmune encephalomyelitis (E...

    **aoyan Zhou, **aoli Liu, Li Liu, Chao Han, Zhaohong **e… in Neurochemical Research (2020)

  7. No Access

    Article

    Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism

    The antinociceptive effects of spirocyclopiperazinium salt compound DXL-A-24 on neuropathic pain and chemical-stimulated pain were investigated in this study. After the administration of DXL-A-24, the paw with...

    Ding Wang, Hua Yang, Yingying Liang, **n Wang, **aolei Du… in Neurochemical Research (2019)

  8. No Access

    Article

    Inhibition of SIRT1/2 upregulates HSPA5 acetylation and induces pro-survival autophagy via ATF4-DDIT4-mTORC1 axis in human lung cancer cells

    Sirtuins have emerged as a promising novel class of anti-cancer drug targets. Inhibition of SIRT1 and SIRT2 induces apoptosis in cancer cells and they play multifaceted roles in regulating autophagy. In the pr...

    Ning Mu, Yuanjiu Lei, Yu Wang, Yingying Wang, Qinghui Duan, Guilin Ma… in Apoptosis (2019)

  9. No Access

    Article

    Generation of Human Embryonic Stem Cell Line Expressing zsGreen in Cholinergic Neurons Using CRISPR/Cas9 System

    Lineage specific human embryonic stem cell (hESC) reporter cell line is a versatile tool for biological studies on real time monitoring of differentiation, physiological and biochemical features of special cel...

    **g Zhou, Chencheng Wang, Kunshan Zhang, Yingying Wang, … in Neurochemical Research (2016)

  10. No Access

    Article

    Bcl-2 silencing attenuates hypoxia-induced apoptosis resistance in pulmonary microvascular endothelial cells

    Pulmonary arterial hypertension (PAH) is a life-threatening disorder that ultimately causes heart failure. While the underlying causes of this condition are not well understood, previous studies suggest that t...

    Yongmei Cao, Zhen Jiang, Zhen Zeng, Yu**g Liu, Yuchun Gu, Yingying Ji… in Apoptosis (2016)

  11. No Access

    Article

    A novel oxaliplatin derivative, Ht-2, triggers mitochondrion-dependent apoptosis in human colon cancer cells

    Ht-2 is a novel oxaliplatin derivative previously identified in a compound screen performed by our laboratory. In the present study, we evaluated the antitumor effects of Ht-2 and investigated its underlying ...

    Yingying **ng, Weiwei Bao, **aobo Fan, Kunmei Liu, **aokang Li, Tao ** in Apoptosis (2015)

  12. No Access

    Article

    Effects of Acupuncture on Glycometabolic Enzymes in Multi-infarct Dementia Rats

    Acupuncture has exhibited therapeutic effects on vascular dementia in our previous research. The mechanism of its anti-dementia effects involves energy metabolism. For brain cells, glucose metabolism is almost...

    Lan Zhao, Peng Shen, Yingying Han, Xuezhu Zhang, Kun Nie… in Neurochemical Research (2011)