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  1. Article

    Open Access

    PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib

    Sorafenib is currently the only systemic agent approved for treatment of advanced hepatocellular carcinoma (HCC). However, intrinsic and acquired resistance to sorafenib remains a great challenge with respect ...

    Kai Zhang, **g Chen, Hao Zhou, Ying Chen, Yingru Zhi, Bei Zhang… in Cell Death & Disease (2018)

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  2. Article

    Open Access

    S1PR1 promotes proliferation and inhibits apoptosis of esophageal squamous cell carcinoma through activating STAT3 pathway

    Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide, which lacks effective biomarkers for prognosis. Therefore, it is urgent to explore new potential molecular markers to disc...

    Yan Liu, Yingru Zhi, Haizhu Song… in Journal of Experimental & Clinical Cancer … (2019)

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  3. No Access

    Article

    Circular RNA circSP5 promotes liver metastasis of colorectal cancer via SP5-mediated BAMBI transcription

    Liver metastasis of colorectal cancer (CRC) is a major cause of cancer morbidity and mortality. Circular RNAs (circRNAs) have been widely reported to be implicated in cancer metastasis. This study aims to inve...

    Yingru Zhi, Qingyuan Gao, Zhibing Wang, Yu Dong… in Functional & Integrative Genomics (2023)