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  1. Article

    Open Access

    A novel “prime and pull” strategy mediated by the combination of two dendritic cell-targeting designs induced protective lung tissue-resident memory T cells against H1N1 influenza virus challenge

    Vaccination is still the most promising strategy for combating influenza virus pandemics. However, the highly variable characteristics of influenza virus make it difficult to develop antibody-based universal v...

    Zhannan Wang, Yingkai He, Wenfeng Wang, Yawen Tian… in Journal of Nanobiotechnology (2023)

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  2. No Access

    Article

    Surface-enhanced Raman spectroscopy aptasensor for simultaneous determination of ochratoxin A and zearalenone using Au@Ag core-shell nanoparticles and gold nanorods

    The design and fabrication of a surface-enhanced Raman scattering (SERS) aptasensor for simultaneous detection of zearalenone (ZEN) and ochratoxin A (OTA) in wheat and corn samples is described. The capture an...

    Ruipeng Chen, Shuang Li, Yunfeng Sun, Bingyang Huo, Yating **a… in Microchimica Acta (2021)

  3. No Access

    Article

    Insight on the relationship between the compositions and antimicrobial activities of Osmanthus fragrans Lour. (Oleaceae family) essential oils by multivariable analysis

    The study aims to optimise the extraction method of Osmanthus fragrans Lour. (Thunbergii flower) essential oil (EO) and establish the correlation between its chemical compositions and antimicrobial activities. Th...

    Hui** Zhu, Changxia Sun, Yingkai Tong, Dehui Wang… in European Food Research and Technology (2021)

  4. No Access

    Article

    Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation

    A long-standing mystery shrouds the mechanism by which catalytically repressed receptor tyrosine kinase domains accomplish transphosphorylation of activation loop (A-loop) tyrosines. Here we show that this rea...

    Lingfeng Chen, William M. Marsiglia, Huaibin Chen… in Nature Chemical Biology (2020)

  5. No Access

    Article

    Exploring fragment-based target-specific ranking protocol with machine learning on cathepsin S

    Cathepsin S (CatS), a member of cysteine cathepsin proteases, has been well studied due to its significant role in many pathological processes, including arthritis, cancer and cardiovascular diseases. CatS inh...

    Yuwei Yang, Jianing Lu, Chao Yang… in Journal of Computer-Aided Molecular Design (2019)

  6. No Access

    Article

    DFT study of SF6 decomposed products on Pd–TiO2: gas sensing mechanism study

    Detecting the species and concentrations of SF6 decomposed products is crucial for on-line monitoring the running status of SF6-insulated equipment. TiO2-based gas sensing material shows a great potential in SF6 ...

    Hao Sun, Yingang Gui, Huangli Wei, Yingkai Long, Qian Wang, Chao Tang in Adsorption (2019)

  7. No Access

    Article

    Intrinsic cleavage of RNA polymerase II adopts a nucleobase-independent mechanism assisted by transcript phosphate

    RNA polymerase II (Pol II) utilizes the same active site for polymerization and intrinsic cleavage. Pol II proofreads the nascent transcript via its intrinsic nuclease activity to maintain high transcriptional...

    Carmen Ka Man Tse, Jun Xu, Liang Xu, Fu Kit Sheong, Shenglong Wang… in Nature Catalysis (2019)

  8. No Access

    Article

    The Effect of Number of Porphyrin Polymer Units on Bandgap for ππ* Conjugation and Charge Transfer System Based on Simulation

    This paper discusses the effect of number of units on bandgap for conjugation versus charge transfer system by using a conjugated polymer ([Zn])n and an unconjugated planar push–pull one (AQ–[Zn])n built upon 2,3...

    Sanxiao Zhao, Gang Wang, Yingkai Sun… in Journal of Inorganic and Organometallic Po… (2017)

  9. No Access

    Article

    High mechanical strength hydrogels preparation using hydrophilic reactive microgels as crosslinking agents

    HRM (hydrophilic reactive microgels) hydrogels based on acrylamide and 2-acrylamido-2-methylpropane sulfonic acid were prepared using HRM as a new crosslinking agent. HRM containing double bonds (C=C) were obt...

    Xu** Qin, Fang Zhao, Yingkai Liu, Hongyun Wang… in Colloid and Polymer Science (2009)

  10. No Access

    Chapter

    Ab Initio Quantum Mechanical/Molecular Mechanical Studies of Histone Modifying Enzymes

    Histone proteins that form the nucleosome core are subject to a variety of post-translational transformations. These histone modifications make up the histone code which extends the information in the genetic ...

    Yingkai Zhang in Multi-scale Quantum Models for Biocatalysis (2009)

  11. No Access

    Article

    An unusual isotopic fractionation of boron in synthetic calcium carbonate precipitated from seawater and saline water

    Inorganic calcium carbonate precipitation from natural seawater and saline water at various pH values was carried out experimentally. The results show the clear positive relationships between boron concentrati...

    Yingkai **ao, Shizhen Li, Haizhen Wei, Aide Sun… in Science in China Series B: Chemistry (2006)

  12. No Access

    Article

    Pseudobond ab initio QM/MM approach and its applications to enzyme reactions

    This perspective article mainly focuses on the development and applications of a pseudobond ab initio QM/MM approach to study enzyme reactions. The following aspects of methodology development are discussed: t...

    Yingkai Zhang in Theoretical Chemistry Accounts (2006)

  13. No Access

    Article

    A preliminary experimental study of the boron concentration in vapor and the isotopic fractionation of boron between seawater and vapor during evaporation of seawater

    A laboratory experiment was undertaken to investigate the behaviour of boron at the seawater-air interface under air flow conditions. Dried air at 25 and 35°C was passed over or bubbled through seawater at the...

    Yingkai **ao, G. H. Swihart, Yun **ao, R. D. Vocke in Science in China Series B: Chemistry (2001)

  14. No Access

    Chapter

    Perspective on “Density-functional theory for fractional particle number: derivative discontinuities of the energy”

    This paper provides an overview of the title paper by Perdew, Parr, Levy and Balduz [Phys Rev Lett 49:1691 (1982)]. The title paper extended density functional theory to fractional electron number by an ensemble ...

    Yingkai Zhang, Weitao Yang in Theoretical Chemistry Accounts (2001)

  15. No Access

    Article

    Perspective on “Density-functional theory for fractional particle number: derivative discontinuities of the energy”

    This paper provides an overview of the title paper by Perdew, Parr, Levy and Balduz [Phys Rev Lett 49:1691 (1982)]. The title paper extended density functional theory to fractional electron number by an ensemble...

    Yingkai Zhang, Weitao Yang in Theoretical Chemistry Accounts (2000)